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Auhtors: Babic A, Sasamoto N, Rosner BA, Tworoger SS, Jordan SJ, Risch HA, et al. PMID: 32239218 PMCID: PMC7118668 DOI: 10.1001/jamaoncol.2020.0421 Abstract Importance: Breastfeeding has been associated with a reduced risk of epithelial ovarian cancer in multiple studies, but others showed no association. Whether risk reduction extends beyond that provided by pregnancy alone or differs [...]
Categories: Cancer Care
Tags: Breastfeeding, Ovarian Cancer
Auhtors: Liu W, Wang W, Wang X, Xu C, Zhang N, Di W PMID: 31866467 DOI: 10.1016/j.canlet.2019.12.024 Abstract Despite the high response rate after surgery and platinum-combination chemotherapy, treatment of ovarian cancer remains challenging due to tumor recurrence and metastasis. Tumor-associated macrophages (TAMs) have been linked to cancer progression and metastasis. However, the impact of [...]
Categories: Cancer Care
Tags: Macrophages, Ovarian Cancer
Auhtors: Yuan X, Zhang J, Li D, Mao Y, Mo F, Du W, Ma X PMID: 28698008 DOI: 10.1016/j.ygyno.2017.07.007 Abstract Objective: The role of tumor-associated macrophages (TAMs) in tumor microenvironment remains controversial due to the two different polarized subsets of TAMs. Here, we performed a meta-analysis to evaluate the correlation between subpopulations of TAMs and [...]
Categories: Cancer Care
Tags: Macrophages, Ovarian Cancer, Tumor
Auhtors: Klimp AH, Hollema H, Kempinga C, van der Zee AG, de Vries EG, Daemen T PMID: 11585770 Abstract This study investigates whether and to what extent cyclooxygenase type-2 (COX-2) and inducible nitric oxide-synthase (iNOS), both known to have an immunosuppressive effect, are expressed in human ovarian tumors. Because COX-2 and iNOS can be expressed [...]
Categories: Cancer Care