Authors: Cabral-Marques O, Halpert G, Schimke LF, Ostrinski Y, Vojdani A, Lattin MT PMID: 35264564 PMCID: PMC8907309 DOI: 10.1038/s41467-022-28905-5 Abstract COVID-19 shares the feature of autoantibody production with systemic autoimmune diseases. In order to understand the role of these immune globulins in the pathogenesis of the disease, it is important to explore the autoantibody spectra. [...]

Authors: Arthur JM, Forrest JC, Boehme KW, Kennedy JL, Owens S, Liu J PMID: 34478478 PMCID: PMC8415618 DOI: 10.1371/journal.pone.0257016 Abstract Background: Activation of the immune system is implicated in the Post-Acute Sequelae after SARS-CoV-2 infection (PASC) but the mechanisms remain unknown. Angiotensin-converting enzyme 2 (ACE2) cleaves angiotensin II (Ang II) resulting in decreased activation of [...]

Authors: Wallukat G, Hohberger B, Wenzel K, Furst J, Wallukat A PMID: 33880442 PMCID: PMC8049853 DOI: 10.1016/j.jtauto.2021.100100 Abstract Impairment of health after overcoming the acute phase of COVID-19 is being observed more and more frequently. Here different symptoms of neurological and/or cardiological origin have been reported. With symptoms, which are very similar to the ones [...]

Authors: Wallukat G, Hohberger B, Wenzel K, Furst J, Wallukat A PMID: 33880442 PMCID: PMC8049853 DOI: 10.1016/j.jtauto.2021.100100 Abstract Impairment of health after overcoming the acute phase of COVID-19 is being observed more and more frequently. Here different symptoms of neurological and/or cardiological origin have been reported. With symptoms, which are very similar to the ones [...]

Authors: Wang EY, Mao T, Klein J, Dai Y, Huck JD, Jaycox JR PMID: 33330894 PMCID: PMC7743105 DOI: 10.1101/2020.12.10.20247205 Abstract COVID-19 manifests with a wide spectrum of clinical phenotypes that are characterized by exaggerated and misdirected host immune responses1-8. While pathological innate immune activation is well documented in severe disease1, the impact of autoantibodies on [...]

Authors: Pascolini S, Vannini A, Deleonardi G, Ciordinik M, Sensoli A PMID: 32989903 PMCID: PMC7536986 DOI: 10.1111/cts.12908 Abstract Coronavirus disease 2019 (COVID-19) is often associated with interstitial pneumonia. However, there is insufficient knowledge on the presence of autoimmune serological markers in patients with COVID-19. We analyzed the presence and role of autoantibodies in patients with [...]

Authors: Franke C, Ferse C, Kreye J, Rocco A, Hosp J PMID: 33359380 PMCID: PMC7834471 DOI: 10.1016/j.bbi.2020.12.022 Abstract Background: COVID-19 intensive care patients can present with neurological syndromes, usually in the absence of SARS-CoV-2 in cerebrospinal fluid (CSF). The recent finding of some virus-neutralizing antibodies cross-reacting with brain tissue suggests the possible involvement of specific [...]

Authors: Zuo Y, Estes SK, Ali RA, Gandhi AA, Shi H PMID: 33139519 PMCID: PMC7724273 DOI: 10.1126/scitranslmed.abd3876 Abstract Patients with COVID-19 are at high risk for thrombotic arterial and venous occlusions. Lung histopathology often reveals fibrin-based blockages in the small blood vessels of patients who succumb to the disease. Antiphospholipid syndrome is an acquired and [...]

Authors: Schiaffino MT, Di Natale M, Garcia-Martinez E, Navarro J, Munoz-Blanco JL, Demelo-Rodriguez P PMID: 32738141 PMCID: PMC7454719 DOI: 10.1093/infdis/jiaa485 Abstract Background: During the coronavirus disease 2019 (COVID-19) pandemic, we detected a new immunofluorescence (IF) pattern in serum autoantibody (autoAb) screening of laboratory-confirmed COVID-19 patients. Methods: The IF pattern was composed of liver and gastric [...]

Authors: Levine TD, Kafaie J, Zeidman LA, Saperstein DS, Bland RJ PMID: 31650561 DOI: 10.1002/mus.26748 Abstract Introduction: Causes of small-fiber peripheral neuropathies (SFN) are often undefined. In this study we investigated associations of serum autoantibodies, immunoglobulin G (IgG) vs fibroblast growth factor receptor-3 (FGFR-3), and immunoglobulin M (IgM) vs trisulfated heparan disaccharide (TS-HDS) in cryptogenic [...]