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References

Categories

I-CARE Early Covid (187) I-CARE Flu and RSV (36) I-PREVENT (153) I-RECOVER Long Covid (111) I-RECOVER Post-Vaccine (320) MATH+ (198)

Tags

ACE2 protein (10) acute respiratory distress syndrome (14) Alopecia (7) Anti-inflammatory (9) Antidepressants (9) Ascorbic Acid (12) autoantibodies (10) autophagy (24) Calcifediol (6) Cancer (9) Corticosteroids (9) COVID-19 (270) COVID-19 Vaccines (8) Curcumin (8) Cytokines (12) Depression (10) Famotidine (14) flavonoids (5) Glucocorticoids (7) Hydroxychloroquine (12) Hyperbaric Oxygen Therapy (9) Inflammation (14) ivermectin (47) long COVID (21) Mast Cells (8) Melatonin (20) Methylprednisolone (7) molnupiravir (5) N-Acetylcysteine (6) Non-Invasive Brain Stimulation (8) Omicron (7) Oxytocin (8) Pneumonia (8) quercetin (15) SARS-CoV-2 (72) SARS-CoV-2 mRNA Vaccines (7) Sepsis (18) spermidine (11) Spike Protein (10) Thiamine (7) Thrombosis (9) Tinnitus (12) Vitamin C (28) Vitamin D (10) Zinc (12)
  • Reference: Protective effect of melatonin administration against SARS-CoV-2 infection: A systematic review.

    Published On: December 22, 2021

    Authors: Molina-Carballo A, Palacios-Lopez R, Jerez-Calero A, Agil A PMID: 35723382 PMCID: PMC8929125 DOI: 10.3390/cimb44010003 Abstract according to the World Health Organization (WHO), COVID-19 is an infectious disease caused by the SARS-CoV-2 virus, responsible for an increasing number of cases and deaths. From a preventive and therapeutic point of view, there are two concerns that [...]

    Categories: I-RECOVER Post-Vaccine

    Tags: Melatonin, SARS-CoV-2

  • Reference: The effect of melatonin on thrombosis, sepsis and mortality rate in COVID-19 patients.

    Published On: October 12, 2021

    Authors: Hasan ZT, AlAtrakji MQ, Mehuaiden AK PMID: 34653660 PMCID: PMC8506572 DOI: 10.1016/j.ijid.2021.10.012 Abstract Objectives: This study aimed to determine the effect of melatonin on thrombosis, sepsis, and mortality rate in adult patients with severe coronavirus infection (COVID-19). Methods: This single-center, prospective, randomized clinical trial was conducted from 1 December 2020 to 1 June 2021 [...]

    Categories: I-RECOVER Post-Vaccine

    Tags: COVID-19, Melatonin, Sepsis, Thrombosis

  • Reference: The effect of melatonin on thrombosis, sepsis and mortality rate in COVID-19 patients

    Published On: October 12, 2021

    This study aimed to determine the effect of melatonin on thrombosis, sepsis, and mortality rate in adult patients with severe coronavirus infection (COVID-19).

    Categories: I-CARE Early Covid, MATH+

    Tags: COVID-19, Melatonin, Sepsis, Thrombosis

  • Reference: Melatonin as adjuvant treatment for coronavirus disease 2019 pneumonia patients requiring hospitalization (MAC-19 PRO): a case series

    Published On: August 11, 2021

    Treatment for coronavirus disease 2019 (COVID19) pneumonia remains empirical and the search for therapies that can improve outcomes continues. Melatonin has been shown to have anti-inflammatory, antioxidant, and immune-modulating effects that may address key pathophysiologic mechanisms in the development and progression of acute respiratory distress syndrome (ARDS), which has been implicated as the likely cause of death in COVID19. We aimed to describe the observable clinical outcomes and tolerability of high-dose melatonin (hdM) given as adjuvant therapy in patients admitted with COVID19 pneumonia.

    Categories: I-CARE Early Covid, I-PREVENT

    Tags: Melatonin

  • Reference: Coronavirus-19,Monocyte/Macrophage glycolysis and inhibition by melatonin.

    Published On: May 8, 2021

    Authors: Reiter RR, Sharma R, Castillo R, Marik PE, Rodriguez AD, Cardinali DP Abstract Two highly relevant studies related to SARS-CoV-2 and coronavirus disease (COVID-19) and supporting the use of melatonin to prevent and treat this serious infection were published recently. Campos-Codo and colleagues [1] documented experimentally their claim that drugs which specifically target [...]

    Categories: I-RECOVER Post-Vaccine

    Tags: COVID-19, Melatonin

  • Reference: Efficacy of high dose vitamin C, melatonin and zinc in Iranian patients with acute respiratory syndrome due to Coronavirus infection: A pilot randomized trial.

    Published On: April 5, 2021

    INTRODUCTION: Our aim was to investigate the efficacy of vitamin C, melatonin, and zinc in patients with severe Covid-19.

    Categories: I-CARE Early Covid, MATH+

    Tags: Hypoxemia, ICU, Melatonin, Vitamin C

  • Reference: The effects of melatonin supplementation on sleep quality and assessment of the serum melatonin in ICU patients: A randomized controlled trial

    Published On: December 4, 2020

    To evaluate whether the use of exogenous melatonin affects sleep, reduces the prevalence of delirium, and decreases the need for analgosedation and to assess whether serum melatonin indices correlate with exogenous administration in critically ill patients.

    Categories:

    Tags: Central Nervous System Depressants, Melatonin

  • Reference: Possible prophylactic approach for SARS-CoV-2 infection by combination of melatonin, Vitamin C and Zinc in animals.

    Published On: December 3, 2020

    Authors: Fatima S, Zaidi SS, Alsharidah AS, Alijaser FS, Banu N PMID: 33344529 PMCID: PMC7744567 DOI: 10.3389/fvets.2020.585789 Abstract SARS-CoV-2, an epidemic, causes severe stress in both human and animals and may induce oxidative stress (OS) and increases susceptibility to infection. Domestic animals are found infected by their COVID-2 suffering owners. Chronic immobilization stress (CIS), a [...]

    Categories: MATH+

    Tags: Melatonin, SARS-CoV-2, Vitamin C, Zinc

  • Reference: Melatonin is significantly associated with survival of intubated COVID-19 patients

    Published On: October 18, 2020

    Respiratory distress requiring intubation is the most serious complication associated with coronavirus disease 2019 (COVID-19).

    Categories: MATH+

    Tags: Melatonin

  • Reference: Clinical trials for use of melatonin to fight COVID-19 are urgently needed

    Published On: August 24, 2020

    Konrad KleszczyƄski, Andrzej T Slominski, Kerstin Steinbrink, Russel J Reiter PMID: 32847033 PMCID: PMC7551551 DOI: 10.3390/nu12092561 AbstractThe recent pandemic of COVID-19 has already infected millions of individuals and has resulted in the death of hundreds of thousands worldwide. Based on clinical features, pathology, and the pathogenesis of respiratory disorders induced by this and other highly [...]

    Categories: I-PREVENT

    Tags: immune response, Inflammation, Melatonin

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