FLCCC Alliance


If ivermectin is so effective in COVID-19, why hasn’t it been adopted into national treatment guidelines?2022-08-25T13:08:38-05:00

In fact, many national and regional health ministries around the world have employed or are employing distribution or “test and treat” programs using ivermectin. Read more on ivmstatus.com.

Why does FLCCC suggest ivermectin for COVID-19?2022-08-25T13:08:38-05:00

Since ivermectin was discovered and developed over 40 years ago, it has demonstrated an ability to make historic impacts on global health. It led to the eradication of a “pandemic” of parasitic diseases across multiple continents. These significant impacts earned the developers of ivermectin the 2015 Nobel Prize in Medicine.

More recently, profound antiviral and anti-inflammatory properties have been identified. Studies show that one of ivermectin’s several antiviral properties is that it strongly binds to the spike protein, helping to keep the SARS-CoV2 virus from entering the cell. These effects, along with its multiple abilities to control inflammation, explain the positive trial results already reported.

Ivermectin is most effective as part of a treatment protocol that includes other FDA-approved medications and supplements backed by clinical and observational evidence.

How do you respond to criticism that many of the studies showing ivermectin’s effectiveness were small, poorly designed and executed, or with high risks of bias?2022-08-25T13:08:37-05:00

As all clinical trials suffer from risks of bias in their design and conduct, as assessed by the Cochrane Risk of Bias 2.0 tool, performing meta-analyses can more accurately detect the true effects despite individual trial biases.

One real-time meta-analysis of dozens of studies of ivermectin shows statistically significant improvements for mortalityventilationICU admissionhospitalization, disease progression, recoverycases, and viral clearance. A pooled analysis shows a 63% improvement for early treatment, 39% improvement for late treatment and 83% improvement for prophylaxis. In order to avoid a statistically significant result, the researchers say they need to exclude more than half of the studies.

What about the recent large, randomized controlled trials that seem to show ivermectin is not effective for COVID-19?2022-08-25T13:08:37-05:00

Many of the trials have extreme conflicts of interest and appear to have been designed to fail and predetermined to show ivermectin as ineffective.

Many use a monotherapy (e.g., treatment with only one therapeutic) when our frontline physicians have found ivermectin is most effective as part of a treatment protocol that includes other FDA-approved medications and supplements backed by clinical and observational evidence.

The trials often under-dosed and started treatment far too late, even though in the medical community it is common knowledge that COVID-19 becomes far more difficult to treat the longer a patient has had symptoms. Treating early is imperative.

The TOGETHER trial, for example, studied patients who started treatment up to eight days after the onset of symptoms. ACTIV-6 severely limited the use of ivermectin, administering a dose below what is known to be effective on the variants at the time and received too late (6 days on average) after the onset of symptoms. Despite these obvious shortfalls, in ACTIV-6 there was a statistically significant, albeit modest, impact on time to clinical recovery for patients using ivermectin to treat COVID-19. This effect was prominently seen in the more severe patients in the trial, whose symptoms were reduced by an average of three days with ivermectin. FLCCC physicians have understood for nearly 18 months that ivermectin works best against COVID-19 when administered early, in combination with other therapies and given with a fatty meal for at least 5 days or until symptoms resolve.

Trials of generic medicines that are funded and influenced by profit-driven pharmaceutical companies will always fail. We need an independent system dedicated to conducting well-designed trials and transparent research studies of repurposed generic treatments – not just for COVID-19, but for all diseases that may have safe and affordable remedies. The use of independent research is our only hope of understanding how these medicines can best be used to help patients.

Is ivermectin effective against different variants of the COVID-19 virus?2022-08-25T13:08:37-05:00

Because ivermectin has five different mechanisms of action against coronaviruses, the medication is also effective with different variants of the virus. We adjust our dosage of ivermectin based on emerging research and clinical observations and add additional medications and measures to help make the protocols more effective against the variants. The current protocols can be found on our Treatment Protocols page. Always discuss the protocols first with your own physician. To find a healthcare provider who follows FLCCC protocols, search our directory.

Should ivermectin be taken on a full or empty stomach?2022-08-25T13:08:37-05:00