Authors: Pappa S, Barmparessou Z, Sakka E, Sakkas N, Pappas A PMID: 35330485 PMCID: PMC8950533 DOI: 10.3390/jpm12030486 Abstract Evidence to date suggests that a significant proportion of COVID-19 patients experience adverse psychological outcomes and neuropsychiatric complications. The aim of this study was to evaluate the effect of SARS-CoV-2 infection and subsequent hospitalization on the mental [...]

Authors: Ahmed A, Ghit A, Houjak A, Elkazzaz M DOI: 10.5772/intechopen.102923 Abstract Zinc is a trace metal ion that has a role in both physiological and pathological processes, making it one of the most common and necessary components involved in brain function. Besides, zinc is required for cell proliferation control in a variety of mechanisms, [...]

Authors: Porter C, Favara M, Scott D, Craske MG, Stein A PMID: 33858874 PMCID: PMC8053815 DOI: 10.1136/bmjopen-2021-049653 Abstract Objective: To provide evidence on the effect of the COVID-19 pandemic on the mental health of young people who grew up in poverty in low/middle-income countries (LMICs). Design: A phone survey administered between August and October 2020 [...]

Authors: Mutz J, Edgcumbe DR, Brunoni AR, Fu CH PMID: 29763711 DOI: 10.1016/j.neubiorev.2018.05.015 Abstract We examined the efficacy and acceptability of non-invasive brain stimulation in adult unipolar and bipolar depression. Randomised sham-controlled trials of transcranial direct current stimulation (tDCS), transcranial magnetic stimulation (TMS) and theta-burst stimulation (TBS), without co-initiation of another treatment, were included. We [...]

Authors: Liu S, Sheng J, Li B, Zhang X doi: https://doi.org/10.3389/fnhum.2017.00526 Abstract Non-invasive brain stimulation (NBS) is a promising treatment for major depressive disorder (MDD), which is an affective processing disorder involving abnormal emotional processing. Many studies have shown that repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS) over the prefrontal cortex [...]

Authors: Dunlop K, Hanlon CA, Downar J PMID: 26849183 PMCID: PMC5434820 DOI: 10.1111/nyas.12985 Abstract Major depressive disorder (MDD) and substance use disorders (SUDs) are prevalent, disabling, and challenging illnesses for which new treatment options are needed, particularly in comorbid cases. Neuroimaging studies of the functional architecture of the brain suggest common neural substrates underlying MDD [...]

Authors: McClure D, Greenman SC, Koppulu SS, Varvara M, Yaseen ZS, Galynker II PMID: 26414234 PMCID: PMC4892785 DOI: 10.1097/NMD.0000000000000378 Abstract This double-blind, sham-controlled study sought to investigate the effectiveness of cranial electrotherapy stimulation (CES) for the treatment of bipolar II depression (BD II). After randomization, the active group participants (n = 7) received 2 mA [...]

Authors: Ranjbar E, Kasaei MS, Mohammad-Shirazi M, Shams J, Mostafavi SA PMID: 24130605 PMCID: PMC3796297 Abstract Objective: Major depression is a mood disorder that causes changes in physical activity, appetite, sleep and weight. Regarding the role of zinc in the pathology of depression, the present study was aimed to investigate the effects of zinc supplementation [...]

Authors: Shevchuk N PMID: 17993252 DOI: 10.1016/j.mehy.2007.04.052 Abstract Depression is a debilitating mood disorder that is among the top causes of disability worldwide. It can be characterized by a set of somatic, emotional, and behavioral symptoms, one of which is a high risk of suicide. This work presents a hypothesis that depression may be caused [...]

Authors: Nowak G, Szewczyk B, Pilc A PMID: 16382189 Abstract Unsatisfactory clinical efficacy and a variety of adverse effects of current antidepressant drugs have incited search for better therapy. Zinc, an antagonist of the glutamate/N-methyl-D-aspartate (NMDA) receptor, exhibits antidepressant-like activity in rodent tests/models of depression. Similarly to antidepressants, zinc induces brain derived neurotrophic factor (BDNF) [...]