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Auhtors: Bischoff-Ferrari HA, Willett WC, Manson JE, Dawson-Hughes B, Manz MG, Theller R, et al. PMID: 35821820 PMCID: PMC9261319 DOI: 10.3389/fragi.2022.852643 Abstract Objective: The aim of this study was to test the individual and combined benefit of vitamin D, omega-3, and a simple home strength exercise program on the risk of any invasive cancer. Design: [...]
Categories: Cancer Care
Authors: Murai IH, Fernandes AL, Sales LP, Pinto AJ, Goessler KF. doi: https://doi.org/10.1101/2020.11.16.20232397 Abstract Importance Patients with COVID-19 may exhibit 25-hydroxyvitamin D deficiency, but the beneficial effects of vitamin D3 supplementation in this disease remain to be proven by randomized controlled trials. Objective To investigate the efficacy and safety of vitamin D3 supplementation in patients [...]
Categories: I-CARE Early Covid, I-PREVENT, MATH+
Auhtors: Bischoff-Ferrari HA, Vellas B, Rizzoli R, Kressig RW PMID: 33170239 PMCID: PMC7656284 DOI: 10.1001/jama.2020.16909 Abstract Importance: The benefits of vitamin D, omega-3 fatty acids, and exercise in disease prevention remain unclear. Objective: To test whether vitamin D, omega-3s, and a strength-training exercise program, alone or in combination, improved 6 health outcomes among older adults. [...]
Categories: Cancer Care
Tags: Omega-3, Supplements, Vitamin D
Authors: Arvinte C, Singh M, Marik PE PMID: 32964205 PMCID: PMC7499070 DOI: 10.1016/j.medidd.2020.100064 Abstract Background: The COVID-19 pandemic has placed an enormous and growing burden on the population and health infrastructure, warranting innovative ways to mitigate risk of contracting and developing severe forms of this disease. A growing body of literature raises the issue of [...]
Categories: MATH+
Until treatment and vaccine for coronavirus disease-2019 (COVID-19) becomes widely available, other methods of reducing infection rates should be explored. This study used a retrospective, observational analysis of deidentified tests performed at a national clinical laboratory to determine if circulating 25-hydroxyvitamin D (25(OH)D) levels are associated with severe acute respiratory disease coronavirus 2 (SARS-CoV-2) positivity rates.
Categories: MATH+
Tags: 25-hydroxyvitamin D, RNA, Vitamin D
Authors: Tan CW, Ho LP, Kalimuddin S, Cherng BP, Teh YE PMID: 33039952 PMCID: PMC7832811 DOI: 10.1016/j.nut.2020.111017 Abstract Objectives: The aim of this study was to determine clinical outcomes of older patients with coronavirus (COVID-19) who received a combination of vitamin D, magnesium, and vitamin B12 (DMB) compared with those who did not. We hypothesized [...]
Categories: MATH+
New research provides evidence of an impaired vitamin D gene signature in CD4+ T cells in patients with severe COVID-19. Mechanistically, it is shown that vitamin D alters the epigenetic landscape of CD4+ T cells, as well as inducing key transcription factors such as STAT3, BACH2 and JUN that reduce levels of IFN-γ and increase IL-10. These changes generate pro-resolving TH1 cells that may be beneficial in resolving or preventing severe COVID-19.
Categories: I-PREVENT
Tags: Vitamin D
Authors: Henriquez MS, de Tejada Romero MJ PMID: 32486496 PMCID: PMC7352679 doi: 10.3390/nu12061617 Abstract Vitamin D deficiency is a global health problem due to its high prevalence and its negative consequences on musculoskeletal and extra-skeletal health. In our comparative review of the two exogenous vitamin D supplementation options most used in our care setting, we [...]
Categories: I-CARE Early Covid, I-CARE Flu and RSV, MATH+
Tags: Calcifediol, Vitamin D
To investigate the association between serum 25-hydroxyvitamin D levels and its effect on adverse clinical outcomes, and parameters of immune function and mortality due to a SARS-CoV-2 infection.
Categories: I-PREVENT
Tags: 25-hydroxyvitamin D, Vitamin D