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References

Categories

I-CARE Early Covid (187) I-CARE Flu and RSV (36) I-PREVENT (153) I-RECOVER Long Covid (111) I-RECOVER Post-Vaccine (320) MATH+ (171)

Tags

ACE2 protein (10) acute respiratory distress syndrome (13) Alopecia (7) Anti-inflammatory (8) Antidepressants (9) Ascorbic Acid (9) autoantibodies (10) autophagy (24) Calcifediol (6) Cancer (9) Corticosteroids (8) COVID-19 (255) COVID-19 Vaccines (8) Curcumin (8) Cytokines (10) Depression (10) Famotidine (14) flavonoids (5) Glucocorticoids (6) Hydroxychloroquine (12) Hyperbaric Oxygen Therapy (9) Inflammation (14) ivermectin (46) long COVID (21) Mast Cells (8) Melatonin (20) molnupiravir (5) N-Acetylcysteine (6) Non-Invasive Brain Stimulation (8) Omicron (7) Oxytocin (8) Pneumonia (8) quercetin (15) resveratrol (5) SARS-CoV-2 (72) SARS-CoV-2 mRNA Vaccines (7) Sepsis (15) spermidine (11) Spike Protein (10) Thrombosis (9) Tinnitus (12) Valproic Acid (5) Vitamin C (16) Vitamin D (9) Zinc (12)
  • Reference: Effect of vitamin D3 supplementaion vs placebo on hospital length of stay in patients with severe COVID-19: A multicenter, double-blind, randomized controlled trial.

    Published On: November 17, 2020

    Authors: Murai IH, Fernandes AL, Sales LP, Pinto AJ, Goessler KF. doi: https://doi.org/10.1101/2020.11.16.20232397 Abstract Importance Patients with COVID-19 may exhibit 25-hydroxyvitamin D deficiency, but the beneficial effects of vitamin D3 supplementation in this disease remain to be proven by randomized controlled trials. Objective To investigate the efficacy and safety of vitamin D3 supplementation in patients [...]

    Categories: I-CARE Early Covid, I-PREVENT, MATH+

    Tags: COVID-19, Vitamin D

  • Reference: Vitamin D insufficiency is prevalent in severe COVID-19

    Published On: September 28, 2020

    The COVID-19 disease course is strikingly divergent. Approximately 80-85% of patients experience mild or no symptoms, while the remainder develop severe disease.

    Categories: MATH+

    Tags: Vitamin D

  • Reference: SARS-CoV-2 positivity rates associated with circulating 25- hydroxyvitamin D level. PloS ONE 2020; 15:e0239252

    Published On: September 17, 2020

    Until treatment and vaccine for coronavirus disease-2019 (COVID-19) becomes widely available, other methods of reducing infection rates should be explored. This study used a retrospective, observational analysis of deidentified tests performed at a national clinical laboratory to determine if circulating 25-hydroxyvitamin D (25(OH)D) levels are associated with severe acute respiratory disease coronavirus 2 (SARS-CoV-2) positivity rates.

    Categories: MATH+

    Tags: 25-hydroxyvitamin D, RNA, Vitamin D

  • Reference: Role of the T cell vitamin D receptor in severe COVID-19

    Published On: July 8, 2020

    New research provides evidence of an impaired vitamin D gene signature in CD4+ T cells in patients with severe COVID-19. Mechanistically, it is shown that vitamin D alters the epigenetic landscape of CD4+ T cells, as well as inducing key transcription factors such as STAT3, BACH2 and JUN that reduce levels of IFN-γ and increase IL-10. These changes generate pro-resolving TH1 cells that may be beneficial in resolving or preventing severe COVID-19.

    Categories: I-PREVENT

    Tags: Vitamin D

  • Reference: Cholecalciferol or calcifediol in the management of vitamin D deficiency.

    Published On: May 31, 2020

    Authors: Henriquez MS, de Tejada Romero MJ PMID: 32486496 PMCID: PMC7352679 doi: 10.3390/nu12061617 Abstract Vitamin D deficiency is a global health problem due to its high prevalence and its negative consequences on musculoskeletal and extra-skeletal health. In our comparative review of the two exogenous vitamin D supplementation options most used in our care setting, we [...]

    Categories: I-CARE Early Covid, I-CARE Flu and RSV, MATH+

    Tags: Calcifediol, Vitamin D

  • Reference: Vitamin D sufficiency, a serum 25-hydroxyvitamin D at least 30 ng/ml reduced risk for adverse clinical outcomes in patients with COVID-19 infection.

    Published On: January 1, 2020

    To investigate the association between serum 25-hydroxyvitamin D levels and its effect on adverse clinical outcomes, and parameters of immune function and mortality due to a SARS-CoV-2 infection.

    Categories: I-PREVENT

    Tags: 25-hydroxyvitamin D, Vitamin D

  • Reference: Worldwide vitamin D status. Best Practice & Research Clinical Endocrinology & Metabolism

    Published On: August 5, 2011

    The aim of the present study is to summarize existing literature on vitamin D levels in adults in different continents and different countries worldwide. The best determinant of vitamin D status is the serum concentration of 25-hydroxyvitamin D (25(OH)D).

    Categories: I-PREVENT

    Tags: 25‐HYDROXY VITAMIN D, Calcifediol, Vitamin D, vitamin D 2

  • Reference: Vitamin D: emerging roles in infection and immunity. Expert Review of Antiinfective Therapy

    Published On: December 8, 2010

    In the preantibiotic era, TB of the skin was treated successfully with UV light. By the 1920s, pulmonary TB was being treated with regular sun exposure. During the last decade, basic laboratory research into the antimicrobial actions of vitamin D has provided new insights into these historical observations.

    Categories: I-PREVENT

    Tags: Antimicrobial Cationic Peptides, Ergocalciferols, Nitric Oxide, Vitamin D

  • Reference: 25-hydroxylation of vitamin D3: relation to circulating vitamin D3 under various input conditions.

    Published On: June 1, 2008

    Authors: Heaney RP, Armas LA, Shary JR, Bell NH, Binkley N, Hollis BW PMID: 18541563 DOI: 10.1093/ajcn/87.6.1738 Abstract Background: Neither the efficiency of the 25-hydroxylation of vitamin D nor the steady state relation between vitamin D(3) and 25-hydroxyvitamin D [25(OH)D] has been studied in humans. Objective: We aimed to examine the relation between serum vitamin [...]

    Categories: I-CARE Early Covid, I-CARE Flu and RSV, MATH+

    Tags: Vitamin D

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