Potential Dietary and Lifestyle Interventions for Decreasing Insulin Resistance

Matthew Thomas J. Halma, M.Sc.; Mobeen Syed, M.B.B.S., M.Sc.; Paul E. Marik, M.D.

Type 2 diabetes is a growing concern for large segments of the world, and its incidence is rising rapidly, especially in developing nations. Clinical management of type 2 diabetes focuses on managing blood glucose through the provision of oral hypoglycemic drugs, insulin, and more recently GLP-1 agonists and SGLT-2 inhibitors. The expectation is that this is a progressive disease and that patients will remain on these medications lifelong. Given the significant impact on quality of life that diabetes has, it is important to find ways to manage the symptoms and improve insulin sensitivity. Diabetes, along with cardiovascular disease, cancer, and respiratory diseases account for most non-communicable disease deaths globally. Low-cost and non-invasive treatment of diabetes through diet and supplementation can have significant impacts on global health.