Auhtors: Wang X, Ma H, Gupta S, Heianza Y, Fonseca V, Qi L PMID: 35776011 PMCID: PMC9681613 DOI: 10.1210/clinem/dgac401 Abstract Context: Sleep quality has been related to the risk of diabetes; however, little is known about the prevalence of diabetes in the United States according to the levels of sleep quality. Objective: To examine the [...]

Auhtors: Hwang CY, Choe W, Yoon KS, Ha J, Kim SS, Yeo EJ, Kang I PMID: 36432618 PMCID: PMC9694619 DOI: 10.3390/nu14224932 Abstract The ketone bodies (KBs) β-hydroxybutyrate and acetoacetate are important alternative energy sources for glucose during nutrient deprivation. KBs synthesized by hepatic ketogenesis are catabolized to acetyl-CoA through ketolysis in extrahepatic tissues, followed by [...]

Auhtors: Jo SB, Sung SJ, Choi HS, Park J-S, Hong Y-K, Joe YA PMID: 36305295 PMCID: PMC9622313 DOI: 10.4062/biomolther.2022.122 Abstract Mebendazole (MBZ), a microtubule depolymerizing drug commonly used for the treatment of helminthic infections, has been suggested as a repositioning candidate for the treatment of brain tumors. However, the efficacy of MBZ needs further study [...]

Authors: Zilberman-Itskovich S, Catalogna M, Sasson E, Hadanny A, Lang E, Finci S et al. PMID: 36261911 DOI: 10.1097/01.NAJ.0000897152.36663.7a Abstract According to this study: Hyperbaric oxygen therapy can improve cognitive function, psychiatric symptoms, pain, and fatigue in patients who have post-COVID-19 condition.The beneficial effect of the therapy can be attributed to increased brain perfusion and [...]

Authors: Bek LM, Berentschot JC, Huijts S, Vlake JH, Aerts JG PMID: 36284829 PMCID: PMC9421428 DOI: 10.1183/23120541.00355-2022 Abstract Introduction: A large proportion of patients experience a wide range of sequelae after acute COVID-19, especially after severe illness. The long-term health sequelae need to be assessed. Our objective was to longitudinally assess [...]

Authors: Wolter N, Jassat W, Walaza S, Welch R, Moultrie H, Groome M PMID: 36195617 PMCID: PMC9531215 DOI: 10.1038/s41467-022-33614-0 Abstract Omicron lineages BA.4 and BA.5 drove a fifth wave of COVID-19 cases in South Africa. Here, we use the presence/absence of the S-gene target as a proxy for SARS-CoV-2 variant/lineage for infections diagnosed using the [...]

Authors: Chen JJ, Zeng BY, Lui CC, Chen TY, Chen YW, Tseng PT PMID: 35583323 PMCID: PMC9129164 DOI: 10.1093/qjmed/hcac124 Abstract The COVID-19 vaccine had been recognized as one of the most important weapons to fight COVID-19. However, the COVID-19 vaccine-associated tinnitus, although not a severe adverse event, had attracted the clinicians’ attention gradually.1 Although it [...]

Auhtors: Halilton MT, Hamilton D, Zderic TW PMID: 36034224 PMCID: PMC9404652 DOI: 10.1016/j.isci.2022.104869 Abstract Slow oxidative muscle, most notably the soleus, is inherently well equipped with the molecular machinery for regulating blood-borne substrates. However, the entire human musculature accounts for only ∼15% of the body's oxidative metabolism of glucose at the resting energy expenditure, despite [...]

Auhtors: Ma Y, Xu X, Wu H, Li C, Zhong P, Liu Z, et al. PMID: 36116250 DOI: 10.1016/j.biopha.2022.113706 Abstract Ivermectin has been proposed as a potential anti-inflammatory drug in addition to its antiparasitic activity. Here we investigated the potential role of ivermectin in the pathogenesis of acute lung injury (ALI) using the lipopolysaccharide (LPS)- [...]

Auhtors: Choi YS, Cho HJ, Jung HJ PMID: 36039737 PMCID: PMC9437372 DOI: 10.4196/kjpp.2022.26.5.367 Abstract Gastric cancer stem cells (GCSCs) are a major cause of radioresistance and chemoresistance in gastric cancer (GC). Therefore, targeting GCSCs is regarded as a powerful strategy for the effective treatment of GC. Atorvastatin is a widely prescribed cholesterol-lowering drug that inhibits [...]