Authors: Chen JJ, Zeng BY, Lui CC, Chen TY, Chen YW, Tseng PT

PMID: 35583323 PMCID: PMC9129164 DOI: 10.1093/qjmed/hcac124


The COVID-19 vaccine had been recognized as one of the most important weapons to fight COVID-19. However, the COVID-19 vaccine-associated tinnitus, although not a severe adverse event, had attracted the clinicians’ attention gradually.1 Although it had not been well studied, the vaccination-mediated immune reaction was considered to be one of the major reasons of this adverse event. Therefore, the immune-targeted treatment, such as steroid, was considered to be an effective treatment.2 However, not every patient with COVID-19-associated tinnitus responded well to the steroid treatment.1 In this case report, we present a case with exacerbated tinnitus after her second dosage Pfizer–BioNTech COVID-19 vaccination, who responded well to the repetitive transcranial magnetic stimulation (rTMS) treatment.

Keywords: COVID-19 vaccine, tinnitus