Authors: Chen JJ, Zeng BY, Lui CC, Chen TY, Chen YW, Tseng PT PMID: 35583323 PMCID: PMC9129164 DOI: 10.1093/qjmed/hcac124 Abstract The COVID-19 vaccine had been recognized as one of the most important weapons to fight COVID-19. However, the COVID-19 vaccine-associated tinnitus, although not a severe adverse event, had attracted the clinicians’ attention gradually.1 Although it [...]

Authors: Chen JJ, Zeng BS, Wu CN, Stubbs B, Carvalho AF, Su KP PMID: 32644131 PMCID: PMC7349076 DOI: 10.1001/jamaoto.2020.1497 Abstract Importance: Tinnitus has a prevalence of 10% to 25% and is frequently associated with numerous complications, such as neuropsychiatric disease. Traditional treatments have failed to meet the needs of patients with tinnitus. Noninvasive brain stimulation [...]

Authors: Langguth B, Elgoyhen AB, Cederroth CR PMID: 30044727 DOI: 10.1146/annurev-pharmtox-010818-021556 Abstract Tinnitus is a highly prevalent condition that is associated with hearing loss in most cases. In the absence of external stimuli, phantom perceptions of sounds emerge from alterations in neuronal activity within central auditory and nonauditory structures. Pioneering studies using lidocaine revealed that [...]

Authors: Azevedo AA, Figueirdo rR, Elgoyhen AB, Langguth B, Schlee W PMID: 28983279 PMCID: PMC5613090 DOI: 10.3389/fneur.2017.00494 Abstract Introduction: Tinnitus is the perception of sound in the absence of an external stimulus. It is a frequent condition for which there is as yet no pharmacological treatment approved. Auditory and non-auditory pathways are involved in tinnitus' [...]

Authors: Langguth B PMID: 26261868 DOI: 10.1097/MOO.0000000000000185 Abstract Purpose of review: Tinnitus, the perception of sound in the absence of a corresponding external acoustic stimulus, is a highly prevalent and frequently severely impairing disorder with worldwide impact. In this article after a short overview about epidemiology and pathophysiology the currently available treatment options will be [...]

Authors: Martinez-Devesda P, Waddell A, Perera R, Theodoulou M PMID: 20824844 DOI: 10.1002/14651858.CD005233.pub3 Abstract Background: This is an update of a Cochrane Review originally published in Issue 1, 2007 of The Cochrane Library.Tinnitus is an auditory perception that can be described as the experience of sound, in the ear or in the head, in the [...]

Authors: Langguth B PMID: 19931642 DOI: 10.1016/j.drudis.2009.11.003 Abstract Tinnitus is the conscious perception of a phantom sound in the absence of an external source. For 1 in 100 of the general population, the condition severely affects quality of life. In spite of the fact that the market for a drug indicated for tinnitus relief is [...]

Authors: Hosseinzadeh A, Kamrava SK, Moore BC, Reiter RJ, Ghaznavi HK PMID: 30892162 DOI: 10.2174/1389450120666190319162147 Abstract Tinnitus is a hearing disorder characterized by the perception of sound without external acoustic stimuli, which is caused by damage to the auditory system in response to excessive levels of noise, ototoxic agents and aging. Neural plasticity, oxidative/nitrosative stress [...]

Authors: Zoger S, Svedlund J, Holgers KM PMID: 16415703 DOI: 10.1097/01.jcp.0000195111.86650.19 Abstract Objective: The relationship between tinnitus and anxiety and depressive disorders has been frequently alluded to, but there are few studies on antidepressants in the treatment of tinnitus, and the efficacy of sertraline on severe refractory tinnitus has not been reported. Method: Consecutive tinnitus [...]

Authors: Bahmad FM, Venosa AR, Oliveira CA PMID: 17260879 Abstract Severe disabling tinnitus (SDT) refers to a symptom severe enough to disrupt affected patients' routine and keep them from performing their daily activities. SDT of a predominantly central origin has been treated successfully with benzodiazepines and GABAergic drugs. Our aim was to test the control [...]