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Authors: Chen BM, Cheng TL, Roffler SR PMID: 34469112 DOI: 10.1021/acsnano.1c05922 Abstract Polyethylene glycol (PEG) is a flexible, hydrophilic simple polymer that is physically attached to peptides, proteins, nucleic acids, liposomes, and nanoparticles to reduce renal clearance, block antibody and protein binding sites, and enhance the half-life and efficacy of therapeutic molecules. Some naïve individuals [...]
Categories: I-RECOVER Post-Vaccine
Authors: Mohamed M, Lila AS, Shimizu T, Alaaeldin E, Hussein A, Sarhan HA et al. PMID: 31275462 PMCID: PMC6598536 DOI: 10.1080/14686996.2019.1627174 Abstract A commonly held view is that nanocarriers conjugated to polyethylene glycol (PEG) are non-immunogenic. However, many studies have reported that unexpected immune responses have occurred against PEG-conjugated nanocarriers. One unanticipated response is the [...]
Categories: I-RECOVER Post-Vaccine
Tags: Polyethylene Glycol
Authors: Hamad I, Hunter AC, Szebeni J, Moghimi SM PMID: 18849076 DOI: 10.1016/j.molimm.2008.08.276 Abstract Poly(ethylene glycol) (PEG) is receiving increasing attention as an intravenous therapeutic agent per se in a variety of experimental therapeutics and veterinary settings, such as spinal cord injury and traumatic axonal brain injury. PEG is often perceived to be immunologically safe, [...]
Categories: I-RECOVER Post-Vaccine
Tags: Polyethylene Glycol