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Auhtors: Koike K PMID: 19464104 DOI: 10.1016/j.canlet.2009.04.010 Abstract Hepatitis B virus (HBV) is a small hepatotropic and highly species-specific enveloped DNA virus. The carcinogenicity of this virus has become focused on the X gene and its coded X protein. The X protein itself is unable to bind to DNA directly, but works as a potent [...]
Categories: Cancer Care
Tags: Hepatitis B Virus
Auhtors: Clippinger AJ, Bouchard MJ PMID: 18448529 PMCID: PMC2446973 DOI: 10.1128/JVI.00154-08 Abstract Over 350 million people are chronically infected with hepatitis B virus (HBV), and a significant number of chronically infected individuals develop primary liver cancer. HBV encodes seven viral proteins, including the nonstructural X (HBx) protein. The results of studies with immortalized or transformed [...]
Categories: Cancer Care
Tags: Hepatitis B Virus, Mitochondria
Auhtors: D'Agostino DM, Bernardi P, Chieco-Bianchi L, Ciminale V PMID: 16096000 DOI: 10.1016/S0065-230X(05)94003-7 Abstract Molecular analyses of tumor virus-host cell interactions have provided key insights into the genes and pathways involved in neoplastic transformation. Recent studies have revealed that the human tumor viruses Epstein-Barr virus (EBV), Kaposi's sarcoma-associated herpesvirus (KSHV), human papillomavirus (HPV), hepatitis B [...]
Categories: Cancer Care