Authors: Burakgazi AZ PMID: 35702058 PMCID: PMC9149535 doi: 10.1159/000524205 Abstract COVID-19 has caused several neurological complications by affecting the central and peripheral nervous systems (PNS). Studies on the PNS involvement in COVID-19 are limited. These complications are likely unreported, given the difficulty of obtaining further diagnostic information, such as expert neurologist evaluation, electrodiagnostic testing, and [...]

Authors: Hammond J, Leister-Tebbe H, Gardner A, Abreu P, Bao W, Wisemandle W DOI: 10.1056/NEJMoa2118542 Abstract BACKGROUND Nirmatrelvir is an orally administered severe acute respiratory syndrome coronavirus 2 main protease (Mpro) inhibitor with potent pan–human-coronavirus activity in vitro. METHODS We conducted a phase 2–3 double-blind, randomized, controlled trial in which symptomatic, [...]

The Omicron SARS-CoV-2 variant is responsible for a major wave of COVID-19, with record case counts reflecting high transmissibility and escape from prior immunity. Defining the time course of Omicron viral proliferation and clearance is crucial to inform isolation protocols aiming to minimize disease spread.

Auhtors: Diaz-Resendiz KJ, Benitez-Trinidad AB, Covantes-Rosales CE, Toledo-Ibarra GA PMID: 35355308 PMCID: PMC9088601 DOI: 10.1002/JLB.3MA0322-279RRR Abstract The mitochondrial membrane potential (ΔΨm ) is a parameter often used to determine mitochondrial function; therefore, it can be used to determine the integrity and functionality of cells. A decrement of ΔΨm is implicated in several inflammatory-related pathologies, such [...]

Authors: Zhang Z, Ren JG, Guo JL, An L, Li S, Zhang ZC PMID: 35338068 PMCID: PMC8960464 DOI: 10.1136/bmjopen-2021-059067 Abstract Introduction: COVID-19 is a public health emergency of international concern, which is characterised by rapid and widespread transmission, high mortality and complications. Several studies have shown the benefits of tai chi and qigong for recovery [...]

Authors: Pappa S, Barmparessou Z, Sakka E, Sakkas N, Pappas A PMID: 35330485 PMCID: PMC8950533 DOI: 10.3390/jpm12030486 Abstract Evidence to date suggests that a significant proportion of COVID-19 patients experience adverse psychological outcomes and neuropsychiatric complications. The aim of this study was to evaluate the effect of SARS-CoV-2 infection and subsequent hospitalization on the mental [...]

Authors: Marforio TD, Mattioli EJ, Zerbetto F, Calvaresi M PMID: 35335283 PMCID: PMC8955646 DOI: 10.3390/molecules27061916 Abstract The persistency of COVID-19 in the world and the continuous rise of its variants demand new treatments to complement vaccines. Computational chemistry can assist in the identification of moieties able to lead to new drugs to fight the disease. [...]

Authors: Cabral-Marques O, Halpert G, Schimke LF, Ostrinski Y, Vojdani A, Lattin MT PMID: 35264564 PMCID: PMC8907309 DOI: 10.1038/s41467-022-28905-5 Abstract COVID-19 shares the feature of autoantibody production with systemic autoimmune diseases. In order to understand the role of these immune globulins in the pathogenesis of the disease, it is important to explore the autoantibody spectra. [...]

Authors: Puskarich MA, Ingraham NE, Merck LH, Driver BE, Wacker DA, Black LP PMID: 35294537 PMCID: PMC8928006 DOI: 10.1001/jamanetworkopen.2022.2735 Abstract Importance: SARS-CoV-2 viral entry may disrupt angiotensin II (AII) homeostasis, contributing to COVID-19 induced lung injury. AII type 1 receptor blockade mitigates lung injury in preclinical models, although data in humans with COVID-19 remain mixed. [...]

Authors: Nguyen B, Tosti A PMID: 35224518 PMCID: PMC8860672 DOI: 10.1016/j.jdin.2022.02.006 Abstract Background: COVID-19 is associated with androgenetic alopecia (AGA), telogen effluvium (TE), and alopecia areata (AA). No studies have analyzed the aggregate data to date. Objective: We conducted a systematic review to characterize the types, incidence, timing, and clinical outcomes of COVID-19-associated alopecia. Methods: [...]