Authors: Cuesta-Llavona E, Gomez J, Albaiceta GM, Amado-Rodriguez L, Garcia-Clemente M PMID: 34116286 PMCID: PMC8169316 DOI: 10.1016/j.intimp.2021.107825 Abstract The chemokine receptor CCR5 has been implicated in COVID-19. CCR5 and its ligands are overexpressed in patients. The pharmacological targeting of CCR5 would improve the COVID-19 severity. We sought to investigate the role of the CCR5-Δ32 variant [...]

Authors: Patterson BK, seethamraju H, Dhody K, Corley MJ, Kazempour K, Lalezari J et al. PMID: 33186704 PMCID: PMC7654230 DOI: 10.1016/j.ijid.2020.10.101 Abstract Objective: Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is now a global pandemic. Emerging results indicate a dysregulated immune response. Given the role of CCR5 in immune cell migration and inflammation, [...]