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Authors: Fontana F, Cazzato S, Giovanella S, Ballestri M, Leonelli M, Mori G PMID: 32838081 PMCID: PMC7363608 DOI: 10.1016/j.ekir.2020.07.008 Abstract Kidney dysfunction is frequently reported in patients with coronavirus disease 2019 (COVID-19). A recent large cohort study described an incidence of acute kidney injury (AKI) of 36% in patients who were hospitalized with COVID-19; AKI [...]
Categories: I-RECOVER Long Covid
Tags: COVID-19, oxalate nephropathy, Vitamin C
Authors: Hannan A, Rahman A, Rahman S, Sohag AA, Dash R, Uddin J. PMID: 32659267 PMCID: PMC7351063 DOI: 10.1016/j.imlet.2020.07.001 Abstract Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is the causative pathogen of deadly Coronavirus disease-19 (COVID-19) pandemic, which emerged as a major threat to public health across the world. Although there is no clear gender or [...]
Categories: I-RECOVER Long Covid, I-RECOVER Post-Vaccine
Tags: autophagy, intermittent fasting, SARS-CoV-2
Authors: Carfi A, Bernabei R, Landi F doi:10.1001/jama.2020.12603 Abstract In Italy, a large proportion of patients with coronavirus disease 2019 (COVID-19) presented with symptoms (71.4% of 31 845 confirmed cases as of June 3, 2020).1 Common symptoms include cough, fever, dyspnea, musculoskeletal symptoms (myalgia, joint pain, fatigue), gastrointestinal symptoms, and anosmia/dysgeusia.2-4 However, information is lacking on [...]
Categories: I-RECOVER Long Covid
This case series describes COVID-19 symptoms persisting a mean of 60 days after onset among Italian patients previously discharged from COVID-19 hospitalization.
Categories: I-RECOVER Long Covid
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Authors: Calis Z, Mogulkoc R, Baltaci AK. PMID: 31288717 DOI: 10.2174/1389557519666190617150051 Abstract The inflammatory process in the human body is a physiological response involving many cellular types and mediators. It results in scar formation to separate the damaged area from the surrounding healthy tissue. Because of increased blood-brain barrier permeability following inflammation, leukocytes infiltrate the [...]
Categories: I-CARE Early Covid, I-CARE Flu and RSV, I-PREVENT, I-RECOVER Long Covid, I-RECOVER Post-Vaccine
Tags: flavonoids, Neuroinflammation
Authors: Seifirad S PMID: 32575019 PMCID: PMC7297676 DOI: 10.1016/j.mehy.2020.110005 Abstract Cytokine storm, multiorgan failure, and particularly acute respiratory distress syndrome (ARDS) is the leading cause of mortality and morbidity in patients with COVID-19. A fulminant ARDS kills the majority of COVID-19 victims. Pirfenidone (5-methyl-1-phenyl-2-[1H]-pyridone), is a novel anti-fibrotic agent with trivial adverse effects. Pirfenidone is [...]
Categories: I-RECOVER Long Covid
Tags: COVID-19, pirfenidone
Authors: Reiter RJ, Sharma R, Ma Q, Liu C, Manucha W, Abreu-Gonzalez P DOI: https://doi.org/10.32794/mr11250068 Abstract COVID-19 has infected hundreds of thousands and killed tens of thousands of people worldwide and it continues to ravage societies as well as fiscal and economic stability of several countries. Currently, several drugs that were designed for other [...]
Categories: I-RECOVER Long Covid, I-RECOVER Post-Vaccine
Tags: COVID-19, Glucose Metabolism, Melatonin
Authors: Unal G, Turan B, Balcioglu YH PMID: 32498007 PMCID: PMC7255327 DOI: 10.1016/j.mehy.2020.109891 Abstract Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) which leads to COVID-19, was first seen in Wuhan province of China in December 2019 and spread globally in a short time. COVID-19 was announced as a pandemic by WHO on March 11th, 2020 and approximately [...]
Categories: I-RECOVER Long Covid, I-RECOVER Post-Vaccine
Tags: COVID-19, Valproic Acid
Authors: Bryce C, Grimes Z, Pujadas E, Ahuja S, Beasley MB, Albrecht R et al. PMID: 33795830 PMCID: PMC8015313 DOI: 10.1038/s41379-021-00793-y Abstract BACKGROUND Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) and its associated clinical syndrome COVID-19 are causing overwhelming morbidity and mortality around the globe, disproportionately affecting New York City. A comprehensive, integrative autopsy series that [...]
Categories: I-RECOVER Long Covid, MATH+
Tags: COVID-19, pathophysiology, SARS-CoV-2
Authors: George PM, Wells AU, Jenkins RG PMID: 32422178 PMCID: PMC7228727 DOI: 10.1016/S2213-2600(20)30225-3 Abstract In December, 2019, reports emerged from Wuhan, China, of a severe acute respiratory disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). By the end of April, 2020, over 3 million people had been confirmed infected, with over 1 million [...]
Categories: I-RECOVER Long Covid, MATH+
Tags: COVID-19, pulmonary fibrosis