Authors: Arbel R, Sagy YW, Hoshen M, Battat E, Lavie G, Sergienko R et al. PMID: 36001529 PMCID: PMC9454652 DOI: 10.1056/NEJMoa2204919 Abstract Background: The oral protease inhibitor nirmatrelvir has shown substantial efficacy in high-risk, unvaccinated patients infected with the B.1.617.2 (delta) variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Data regarding the effectiveness of [...]

Auhtors: Akhgarjand C, Asoudeh F, Bagheri A, Kalantar Z, Vahabi Z, Shab-Bidar S, et al. PMID: 36017529 DOI: 10.1002/ptr.7598 Abstract Clinical trial studies revealed conflicting results on the effect of Ashwagandha extract on anxiety and stress. Therefore, we aimed to evaluate the effect of Ashwagandha supplementation on anxiety as well as stress. A systematic search [...]

Authors:Baxter AL, Schwartz KR, Johnson RW, Srinivasa AS. PMID:36007135 DOI: 10.1177/01455613221123737 Abstract Objective: To determine whether initiating saline nasal irrigation after COVID-19 diagnosis reduces hospitalization and death in high-risk outpatients compared with observational controls, and if irrigant composition impacts severity. Methods: Participants 55 and older were enrolled within 24 hours of a + PCR COVID-19 [...]

Authors: Cadegiani FA PMID: 35971401 PMCID: PMC9372380 DOI: 10.7759/cureus.27883 Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mRNA vaccine-induced myocarditis is a rare but well-documented complication in young males. The increased incidence of sudden death among athletes following vaccination has been reported and requires further investigation. Whether the risk of myocarditis, [...]

Auhtors: Evangeliou AE, Spilioti MG, Vassilakou D, Goutsaridou F, Seyfried TN PMID: 36059366 PMCID: PMC9435310 DOI: 10.7759/cureus.27603 Abstract A high-fat and low-carbohydrate diet was administered as a complementary and alternative therapy to a 54-year-old man suffering from non-small-cell lung cancer (NSCLC) with brain metastasis. Three months after the cessation of chemotherapy and radiotherapy, a ketogenic [...]

Authors: Wimalawansa SJ. PMID: 35889955 PMCID: PMC9319502 DOI: 10.3390/nu14142997 Abstract Vitamin D deficiency is a global public health problem, a pandemic that commonly affects the elderly and those with comorbidities such as obesity, diabetes, hypertension, respiratory disorders, recurrent infections, immune deficiency, and malignancies, as well as ethnic minorities living in temperate countries. The same groups [...]

Auhtors: Wimalawansa SJ PMID: 35889955 PMCID: PMC9319502 DOI: 10.3390/nu14142997 Abstract Vitamin D deficiency is a global public health problem, a pandemic that commonly affects the elderly and those with comorbidities such as obesity, diabetes, hypertension, respiratory disorders, recurrent infections, immune deficiency, and malignancies, as well as ethnic minorities living in temperate countries. The same groups [...]

Authors: Parvez SA, Saha MK, Araf Y, Islam T, Ohtsuki G PMID: 35759231 PMCID: PMC9210926 DOI: 10.1002/iid3.639 Abstract Introduction: Prominently accountable for the upsurge of COVID-19 cases as the world attempts to recover from the previous two waves, Omicron has further threatened the conventional therapeutic approaches. The lack of extensive research regarding Omicron has raised [...]

Auhtors: Sadrekarimi H, Gardanova ZR, Bakhshesh M, Ebrahimzadeh F, Yaseri AF, Thangavelu L, et al. PMID: 35794566 PMCID: PMC9258144 DOI: 10.1186/s12967-022-03492-7 Abstract In recent years, there has been a greater emphasis on the impact of microbial populations inhabiting the gastrointestinal tract on human health and disease. According to the involvement of microbiota in modulating physiological [...]

Authors: Freitag K, Sterczyk N, Wendlinger S, Schulz J, Ralser M, Fleck L et al. PMID: 35780157 PMCID: PMC9250727 DOI: 10.1186/s12974-022-02534-7 Abstract Background: Deposition of amyloid beta (Aβ) and hyperphosphorylated tau along with glial cell-mediated neuroinflammation are prominent pathogenic hallmarks of Alzheimer's disease (AD). In recent years, impairment of autophagy has been identified as another [...]