Authors: Wang W, Sun C, Mao L, Ma P, Liu F, Yang J. doi: https://doi.org/10.1016/j.tifs.2016.07.004 Abstract Background Quercetin, one of the most well-known flavonoids, has been included in human diet for a long history. The use of quercetin has been widely associated with a great number of health benefits, including antioxidant, anti-inflammatory, antiviral and anticancer [...]

Authors: Li Y, Yao J, Han C, Yang J, Chaudhry MT, Wang S et al. PMID: 26999194 doi: 10.3390/nu8030167 Abstract In vitro and some animal models have shown that quercetin, a polyphenol derived from plants, has a wide range of biological actions including anti-carcinogenic, anti-inflammatory and antiviral activities; as well as attenuating lipid peroxidation, platelet [...]

Authors: Dabbagh-Bazarbachi H, Clergeaud G, Quesada IM, Ortiz M, O'Sullivan CK PMID: 25050823 DOI: 10.1021/jf5014633 Abstract Labile zinc, a tiny fraction of total intracellular zinc that is loosely bound to proteins and easily interchangeable, modulates the activity of numerous signaling and metabolic pathways. Dietary plant polyphenols such as the flavonoids quercetin (QCT) and epigallocatechin-gallate act [...]

Authors: Weng Z, Zhang B, Asadi S, Sismanopoulos N, Butcher A. PMID: 22470478 PMCID: PMC3314669 DOI: 10.1371/journal.pone.0033805 Abstract Mast cells are immune cells critical in the pathogenesis of allergic, but also inflammatory and autoimmune diseases through release of many pro-inflammatory cytokines such as IL-8 and TNF. Contact dermatitis and photosensitivity are skin conditions that involve [...]

Authors: Wikramanayake TC, Villasante AC, Mauro LM, Perez CI, Jimenez JJ PMID: 22042611 PMCID: PMC3273564 DOI: 10.1007/s12192-011-0305-3 Abstract Alopecia areata (AA) is an autoimmune non-scarring hair loss disorder. AA can be acute, recurrent, or chronic. Current therapeutic options for AA are limited, and there is no effective prevention for recurrent AA. We have previously shown [...]