Auhtors: Tseng CH PMID: 30896668 PMCID: PMC6709307 DOI: 10.1097/MD.0000000000014955 Abstract Background: The relationship between metformin use and the risk of prostate cancer is still inconclusive. Therefore, we performed a systematic review and meta-analysis of all eligible cohort studies to evaluate a potential association of metformin use with prostate cancer risk. Methods: A comprehensive literature search [...]

Auhtors: Zhang P, Li H, Tan X, Chen L, Wang S PMID: 29618465 DOI: 10.1158/1055-9965.EPI-17-0936 Abstract Background: Preclinical data suggest that metformin may reduce breast cancer incidence and improve cancer prognosis. However, the current evidence in observational studies is inconclusive. A systematic review and meta-analysis was conducted to assess the effect of metformin on the [...]

Auhtors: Gandini S, Puntoni M, Heckman-Stoddard BM, Dunn BK, Ford L, DeCensi A, Szabo E PMID: 24985407 PMCID: PMC4154969 DOI: 10.1158/1940-6207.CAPR-13-0424 Abstract Previous meta-analyses have shown that the antidiabetic agent metformin is associated with reduced cancer incidence and mortality. However, this effect has not been consistently demonstrated in animal models and recent epidemiologic studies. We [...]