Auhtors: Mukherjee P, Greenwood B, Henao J, Kiebish MA, Seyfried TN doi: https://doi.org/10.1101/2023.06.09.544252 Abstract Invasion of high-grade glioma (HGG) cells through the brain and spinal cord is a leading cause of cancer death in children. Despite advances in treatment, survivors often suffer from life-long adverse effects of the toxic therapies. This study investigated the influence [...]

Auhtors: Evangeliou AE, Spilioti MG, Vassilakou D, Goutsaridou F, Seyfried TN PMID: 36059366 PMCID: PMC9435310 DOI: 10.7759/cureus.27603 Abstract A high-fat and low-carbohydrate diet was administered as a complementary and alternative therapy to a 54-year-old man suffering from non-small-cell lung cancer (NSCLC) with brain metastasis. Three months after the cessation of chemotherapy and radiotherapy, a ketogenic [...]

Auhtors: Mukherjee P, Augur ZM, Li M, Hill C, Greenwood B, Domin MA, et al. Abstract Glioblastoma (GBM) is an aggressive primary human brain tumour that has resisted effective therapy for decades. Although glucose and glutamine are the major fuels that drive GBM growth and invasion, few studies have targeted these fuels for therapeutic management. [...]

Auhtors: Augustin K, Khabbush A, Williams S, Eaton S, Orford M, Cross JH, et al. PMID: 29263011 DOI: 10.1016/S1474-4422(17)30408-8 Abstract High-fat, low-carbohydrate diets, known as ketogenic diets, have been used as a non-pharmacological treatment for refractory epilepsy. A key mechanism of this treatment is thought to be the generation of ketones, which provide brain cells [...]

Auhtors: Winters N, Kelley JH Abstract "Read this important book to learn how cancer is an environmental, metabolic disease with many small causes that stack up―and what you can do to prevent or even reverse it."―Dave Asprey, New York Times bestselling author of The Bulletproof Diet The Optimal Terrain Ten Protocol to Reboot Cellular Health! [...]

Auhtors: Zhou W, Mukherjee P, Kiebish MA, Markis WT, Mantis JG, Seyfried TN PMID: 17313687 PMCID: PMC1819381 DOI: 10.1186/1743-7075-4-5 Abstract Background: Malignant brain cancer persists as a major disease of morbidity and mortality in adults and is the second leading cause of cancer death in children. Many current therapies for malignant brain tumors fail to [...]