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Authors: Bek LM, Berentschot JC, Huijts S, Vlake JH, Aerts JG PMID: 36284829 PMCID: PMC9421428 DOI: 10.1183/23120541.00355-2022 Abstract Introduction: A large proportion of patients experience a wide range of sequelae after acute COVID-19, especially after severe illness. The long-term health sequelae need to be assessed. Our objective was to longitudinally assess [...]
Categories: I-RECOVER Long Covid
Tags: COVID-19, long COVID, symptoms
Authors: Ma WH, Zhang XG, Guo LL, Zhang JB, Wei FT PMID: 34109585 DOI: 10.26355/eurrev_202105_25944 Abstract Objective: Experimental autoimmune myocarditis (EAM) is characterized by pronounced macrophage infiltration, cardiac necrosis, and cardiac fibrosis. Our previous studies have demonstrated that suppressed androgen receptor (AR) enables anti-inflammation to promote tissue repair by decreasing M1 macrophages and increasing M2 [...]
Categories: I-RECOVER Long Covid
Tags: autophagy
Reference: A raising dawn of pentoxifylline in the management of inflammatory disorders in Covid-19.
Authors: Mostafa-Hedeab G, Al-kuraishy HM, Al-Gareeb AA, Jeandet P, Saaad HM, El-Saber Batiha G PMID: 35486310 PMCID: PMC9051499 DOI: 10.1007/s10787-022-00993-1 Abstract The existing pandemic viral infection caused by severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) leads to coronavirus disease 2019 (Covid-19). SARS-CoV-2 exploits angiotensin-converting enzyme 2 (ACE2) as an entry-point into affected cells and [...]
Categories: I-RECOVER Long Covid, I-RECOVER Post-Vaccine
Tags: COVID-19, Pentoxifylline
Authors: Voruz P, Allali G, Benzakour L, Jacot I, Pierce J doi: https://doi.org/10.3390/ctn6020009 Abstract There is growing awareness that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, even in its mild or moderate respiratory forms, can include long-term neuropsychological deficits. Standardized neuropsychological, psychiatric, neurological, and olfactory tests were administered to 45 patients 236.51 ± 22.54 [...]
Categories: I-RECOVER Long Covid
Tags: long COVID, neuropsychological
Authors: Cabral-Marques O, Halpert G, Schimke LF, Ostrinski Y, Vojdani A, Lattin MT PMID: 35264564 PMCID: PMC8907309 DOI: 10.1038/s41467-022-28905-5 Abstract COVID-19 shares the feature of autoantibody production with systemic autoimmune diseases. In order to understand the role of these immune globulins in the pathogenesis of the disease, it is important to explore the autoantibody spectra. [...]
Categories: I-RECOVER Long Covid, I-RECOVER Post-Vaccine
Tags: autoantibodies, COVID-19
Authors: Zhao Y, Jia M, Chen W, Liu Z PMID: 35218914 DOI: 10.1016/j.freeradbiomed.2022.02.021 Abstract Intermittent fasting (IF) has been studied for its effects on lifespan and the prevention or delay of age-related diseases upon the regulation of metabolic pathways. Mitochondria participate in key metabolic pathways and play important roles in maintaining intracellular signaling networks that [...]
Categories: I-RECOVER Long Covid, I-RECOVER Post-Vaccine
Tags: intermittent fasting
Authors: Dhooria S, Chaudhary S, Sehgal IS, Agarwal R, Arora S PMID: 34887325 PMCID: PMC8850687 DOI: 10.1183/13993003.02930-2021 Abstract High-dose prednisolone may not be superior to a low-dose 6-week regimen in improving clinical, physiological and radiological outcomes, or health-related quality of life, in patients with symptomatic post-COVID-19 diffuse parenchymal lung abnormalities. Keywords: prednisolone, Long COVID, COVID-19 [...]
Categories: I-RECOVER Long Covid
Tags: Prednisone
Authors: Izquierdo JL, Soriano JB, Gonzalez Y, Lumbreras S PMID: 35084258 PMCID: PMC8795755 DOI: 10.1177/00368504221074574 Abstract Infection by SARS-CoV-2 causing coronavirus disease 2019 (COVID-19) can be associated with serious and life-threatening conditions, including acute respiratory distress syndrome (ARDS). Severity and mortality have been related to a cytokine storm, an imbalance of oxidative stress, and a [...]
Categories: I-CARE Early Covid, I-RECOVER Long Covid, I-RECOVER Post-Vaccine, MATH+
Tags: COVID-19, N-Acetylcysteine
Authors: Patterson BK, Francisco EB, Yogendra R, Long E, Pise A, Hall E et al. PMID: 35082777 PMCID: PMC8784688 DOI: 10.3389/fimmu.2021.746021 AbstractThe recent COVID-19 pandemic is a treatment challenge in the acute infection stage but the recognition of chronic COVID-19 symptoms termed post-acute sequelae SARS-CoV-2 infection (PASC) may affect up to 30% of all infected [...]
Categories: I-RECOVER Long Covid, I-RECOVER Post-Vaccine
Tags: COVID-19
Authors:Michelen M, Manoharan L, Elkheir N, Cheng V, Dagens D, Hastie C. . PMID: PMC8478580 DOI: 10.1136/bmjgh-2021-005427 Abstract Background: While it is now apparent clinical sequelae (long COVID) may persist after acute COVID-19, their nature, frequency and aetiology are poorly characterised. This study aims to regularly synthesise evidence on long COVID characteristics, to help inform [...]
Categories: I-RECOVER Long Covid
Tags: COVID-19, long COVID