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Auhtors: Munoz A, Grant WB PMID: 35406059 PMCID: PMC9003337 DOI: 10.3390/nu14071448 Abstract This is a narrative review of the evidence supporting vitamin D's anticancer actions. The first section reviews the findings from ecological studies of cancer with respect to indices of solar radiation, which found a reduced risk of incidence and mortality for approximately 23 [...]
Categories: Cancer Care
Auhtors: Chi JT, Lin PH, Tolstikov V, Howard L, Chen EY, Bussberg V, et al. PMID: 35338353 DOI: 10.1038/s41391-022-00525-6 Abstract Background: Systemic treatments for prostate cancer (PC) have significant side effects. Thus, newer alternatives with fewer side effects are urgently needed. Animal and human studies suggest the therapeutic potential of low carbohydrate diet (LCD) for [...]
Categories: Cancer Care
Tags: Carbohydrate Diet, Ketogenesis
Auhtors: Kumari N, Choi SH PMID: 35183252 PMCID: PMC8857848 DOI: 10.1186/s13046-022-02272-x Abstract Cancer immunotherapy has emerged as a novel cancer treatment, although recent immunotherapy trials have produced suboptimal outcomes, with durable responses seen only in a small number of patients. The tumor microenvironment (TME) has been shown to be responsible for tumor immune escape and [...]
Categories: Cancer Care
Tags: Macrophages, Tumor
Auhtors: Vasim I, Majeed CN, DeBoer MD PMID: 35276989 PMCID: PMC8839325 DOI: 10.3390/nu14030631 Abstract Given the ongoing strain that the obesity epidemic has placed on public health outcomes, new and effective approaches to weight control are needed. One approach to improving weight and metabolic outcomes is intermittent fasting, which consists of multiple different timing schedules [...]
Categories: Cancer Care
Auhtors: Pliss A, Kuzmin AN, Prasad PN, Mahajan SD PMID: 35049274 PMCID: PMC8790819 DOI: 10.1021/acschemneuro.1c00675 Abstract The SARS-CoV-2 virus is notorious for its neuroinvasive capability, causing multiple neurological conditions. The neuropathology of SARS-CoV-2 is increasingly attributed to mitochondrial dysfunction of brain microglia cells. However, the changes in biochemical content of mitochondria that drive the progression [...]
Categories: Cancer Care
Auhtors: Noman MZ, Desantis G, Janji B, Hasmim M, Karray S, Dessen P, et al. PMID: 35053426 PMCID: PMC8774531 DOI: 10.3390/cells11020310 Abstract Myeloid-derived suppressor cells (MDSCs) are one of the main suppressive cell population of the immune system. They play a pivotal role in the establishment of the tumor microenvironment (TME). In the context of [...]
Categories: Cancer Care
Tags: Tumor
Auhtors: Ma T, Renz BW, Ilmer M, Koch D, Yang Y, Werner J, Bazhin AV PMID: 35053426 PMCID: PMC8774531 DOI: 10.3390/cells11020310 Abstract Myeloid-derived suppressor cells (MDSCs) are one of the main suppressive cell population of the immune system. They play a pivotal role in the establishment of the tumor microenvironment (TME). In the context of [...]
Categories: Cancer Care
Tags: Tumor
Auhtors: Abrams HR, Durbin S, Huang CX, Johnson SF, Nayak RK, Zahner GJ, Peppercorn J PMID: 34850932 DOI: 10.1093/tbm/ibab091 Abstract Financial toxicity describes the financial burden and distress that can arise for patients, and their family members, as a result of cancer treatment. It includes direct out-of-pocket costs for treatment and indirect costs such as [...]
Categories: Cancer Care
Tags: Cancer
Auhtors: Medini H, Zirmman A, Mishmar D PMID: 34812416 PMCID: PMC8599136 DOI: 10.1016/j.isci.2021.103471 Abstract Mitochondria are pivotal for bioenergetics, as well as in cellular response to viral infections. Nevertheless, their role in COVID-19 was largely overlooked. Here, we analyzed available bulk RNA-seq datasets from COVID-19 patients and corresponding healthy controls (three blood datasets, N = [...]
Categories: Cancer Care
Tags: COVID-19, Mitochondria
Auhtors: Pasvol TJ, Macgregor EA, Rait G, Horsfall L PMID: 34782337 PMCID: PMC9279840 DOI: 10.1136/bmjsrh-2021-201260 Abstract Background: Over the last 20 years, new contraceptive methods became available and incentives to increase contraceptive uptake were introduced. We aimed to describe temporal trends in non-barrier contraceptive prescribing in UK primary care for the period 2000-2018. Methods: A [...]
Categories: Cancer Care
Tags: Contraceptive