There are around 50 million cases of sepsis per year globally, and 1 in 5 deaths is associated with sepsis. Sepsis is a time-sensitive disease, and treatment should begin before a diagnosis is confirmed. These 8 clinical tips will help you manage and treat your hospitalized sepsis patients.
- Do not wait for the diagnosis to begin treatment with antibiotics.
- To diagnose sepsis, a clinician should check these labs:
• Blood cultures
• PCT (precalcitonin)
• CBC with differential
• Ferritin
• Electrolyte panel with attention to monitoring
• Magnesium - It is important to note that too much fluid will increase mortality of the septic patient.
- For the patient that needs support of the vascular system, a norepinephrine infusion is recommended. The FLCCC MHAT Treatment Protocol should be used as the guide for treatment. The FLCCC MHAT Protocol includes melatonin, hydrocortisone, ascorbic acid (vitamin C), and thiamine.
- Melatonin 6-10 mg every night.
- Hydrocortisone 50 mg every 6 hours for 4 days and until the patient is off vasopressors. (Note: If treatment is less than 10 days, tapering the dose is not needed).
- Vitamin C 1.5 gms IV every 6 hrs for 12-16 IV doses. See our Sepsis Protocol for more detailed information at link below.
- Thiamine 200 mg IV every 12 hours.
For more information on the Sepsis Care Protocol:
For more information about the nutraceuticals in the MHAT Protocol:
