Authors: Hekimian G, Kerneis M, Zeitouni M, Cohen-Aubart F, Chommeloux J

PMID: 32910974 PMCID: PMC7476896 DOI: 10.1016/j.chest.2020.08.2099

Abstract

Hyperinflammatory shock was described recently in children during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. The clinical presentation of these patients involved fever, cutaneous rash, abdominal symptoms, distributive shock, and acute cardiac injury. This multisystem inflammatory syndrome had similarities with classic, incomplete, or most severe forms of the Kawasaki disease.The frequent troponin elevation and left ventricular dysfunction suggested the presence of acute myocarditis, although description of cardiac MRI is lacking.

This case series describes the clinical presentation, characteristics, and management of the patients over 16 years old with coronavirus disease 2019 (COVID-19) who were admitted for suspected acute or fulminant myocarditis (according to the European Society of Cardiology and the American Heart Association definitions and included multisystem inflammatory syndrome in the adult intensive and acute cardiac care units of a tertiary French center.

Keywords: COVID-19, Myocarditis, Multisystem Inflammatory Syndrome

More on: MATH+

More on: COVID-19 | Myocarditis