Authors: Pantziarka P, Verbaanderd C, Sukhatme V, Rica C, I, Crispino S, Gyawali B, et al.
PMID: 30679953 PMCID: PMC6345075 DOI: 10.3332/ecancer.2018.886
Abstract
Repurposing is a drug development strategy that seeks to use existing medications for new indications. In oncology, there is an increased level of activity looking at the use of non-cancer drugs as possible cancer treatments. The Repurposing Drugs in Oncology (ReDO) project has used a literature-based approach to identify licensed non-cancer drugs with published evidence of anticancer activity. Data from 268 drugs have been included in a database (ReDO_DB) developed by the ReDO project. Summary results are outlined and an assessment of clinical trial activity also described.
Keywords: ReDO project; cancer drugs; drug repurposing; online database; repositioning.
Source: https://pubmed.ncbi.nlm.nih.gov/30679953/
Archive: https://archive.ph/Mg0DY
