Authors: Swank Z, Senussi Y, Alter G, Walt DR

PMID: 36052466 PMCID: PMC10169416 DOI: 10.1093/cid/ciac722


The diagnosis of postacute sequelae of coronavirus disease 2019 (PASC) poses an ongoing medical challenge. To identify biomarkers associated with PASC we analyzed plasma samples collected from PASC and coronavirus disease 2019 patients to quantify viral antigens and inflammatory markers. We detect severe acute respiratory syndrome coronavirus 2 spike predominantly in PASC patients up to 12 months after diagnosis.

Keywords: COVID-19; SARS-CoV-2 antigens; long COVID; post-acute sequelae of COVID-19 (PASC); spike.