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Long Story Short Episode 70: High Fibrinogen and D-Dimers Linked to Long COVID

High Fibrinogen and D-Dimers Linked to Long COVID

In this early pandemic study of COVID-19 confirmed hospitalized patients, researchers found two groups of individuals with biomarker profiles: the first had high fibrinogen levels in relation to C-Reactive proteins (CRP) and the second had an increase in D-Dimers in relation to CRP. These molecules generally increase in relation to CRP; however, here the researchers found that the fibrinogen and D-Dimers increased while the CRP stayed low. These cohorts were associated with higher likelihood of neurological long COVID. Let’s review both the findings and the mechanisms.

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