Authors: Darwin E, Hirt PA, Fertig R, Doliner B, Delcanto G

PMID: 29769777 PMCID: PMC5939003 DOI: 10.4103/ijt.ijt_99_17


Alopecia areata (AA) is a complex autoimmune condition that causes nonscarring hair loss. It typically presents with sharply demarcated round patches of hair loss and may present at any age. In this article, we review the epidemiology, clinical features, pathogenesis, and new treatment options of AA, with a focus on the immunologic mechanism underlying the treatment. While traditional treatment options such as corticosteroids are moderately effective, a better understanding of the disease pathogenesis may lead to the development of new treatments that are more directed and effective against AA. Sources were gathered from PubMed, Embase, and the Cochrane database using the keywords: alopecia, alopecia areata, hair loss, trichoscopy, treatments, pathogenesis, and epidemiology.

Keywords: Alopecia; alopecia areata; alopecia totalis; alopecia universalis; hair loss.

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