Hydroxytyrosol and its effect on health

  • Hydroxytyrosol and its effect on health

    Posted by Xaralare Mioyr on January 20, 2025 at 2:30 am EST

    I’ve heard that hydroxytyrosol is very beneficial for health, but I don’t quite understand how it works. Can it really help with heart disease or skin problems? And is it enough to just add olive oil to my diet to get these benefits?

    vegandan replied 3 days, 1 hour ago 4 Members · 3 Replies
  • 3 Replies
  • IMA-GregT

    Organizer
    January 20, 2025 at 6:20 am EST

    Great question, I’m not medically trained, so this is new to me. Anyone who has experience with Hydroxytyrosol please add your thoughts. Also Mierion drop what you’ve found here as well please.

    Here’s what Perplexity AI says:

    Hydroxytyrosol is a powerful natural antioxidant compound primarily found in olives, olive oil, and olive leaves[1][2]. It is a colorless solid with the chemical formula (HO)2C6H3CH2CH2OH, classified as a phenylethanoid and a derivative of catechol[1][4].

    ## Chemical Properties and Structure

    Hydroxytyrosol is characterized by:

    – Molecular formula: C8H10O3

    – Low molecular weight: 154.17 g/mol

    – Hydrophilic nature, allowing it to dissolve readily in water

    – Ability to cross the blood-brain barrier, unique among polyphenols[2][4]

    ## Sources and Occurrence

    This compound is naturally present in:

    – Olive fruit, pulp, and leaves

    – Extra virgin olive oil

    – Olive mill waste waters

    – Wines (to a lesser extent)[1][2]

    ## Health Benefits

    Hydroxytyrosol has demonstrated numerous potential health benefits:

    1. **Potent Antioxidant Activity**: It has one of the highest known ORAC (oxygen radical absorbance capacity) values among natural antioxidants[2].

    2. **Cardiovascular Protection**: It may reduce the risk of atherosclerosis by decreasing LDL oxidation[2][5].

    3. **Anti-inflammatory Properties**: Studies have shown its ability to reduce inflammatory markers and associated pain[2].

    4. **Antimicrobial Effects**: In vitro experiments demonstrate activity against various pathogens[2].

    5. **Potential Anticancer Activity**: Research suggests it may inhibit proliferation and promote apoptosis of tumor cells[2].

    6. **Skin Protection**: Hydroxytyrosol may help prevent UVA damage to skin cells and reduce oxidative stress[2][3].

    ## Applications

    Hydroxytyrosol finds applications in various industries:

    1. **Cosmetics**: Used in anti-aging formulations, moisturizers, and skin protection products[3][4].

    2. **Nutraceuticals**: Incorporated into dietary supplements for its health benefits[5].

    3. **Food Industry**: Valued for its ability to preserve and enhance nutritional quality of products[4].

    4. **Pharmaceuticals**: Being researched for potential use in cardiovascular disease prevention and cancer treatment[5][6].

    The European Food Safety Authority has concluded that consuming 5 mg of hydroxytyrosol and its derivatives daily may help reduce the risk of cardiovascular diseases[5].

    Citations:

    [1] https://en.wikipedia.org/wiki/Hydroxytyrosol

    [2] https://olivewellnessinstitute.org/article/about-hydroxytyrosol/

    [3] https://www.thepinkfoundry.com/pages/what-is-hydroxytyrosol

    [4] https://www.bio-powder.com/en/glossary/hydroxytyrosol/

    [5] https://pmc.ncbi.nlm.nih.gov/articles/PMC4428486/

    [6] https://www.cancer.gov/publications/dictionaries/cancer-drug/def/hydroxytyrosol

    [7] https://www.ebi.ac.uk/chebi/chebiOntology.do?chebiId=CHEBI%3A68889

  • Stefanie Bernier

    Member
    January 20, 2025 at 10:15 am EST

    Personally, I try to include it in my routine by using high-quality olive oils known to be rich in this compound. I agree that hydroxytyrosol is an incredible antioxidant with numerous health benefits. Incorporating natural sources like olive oil not only enhances my diet but also ensures I reap the cardiovascular and immune system benefits of hydroxytyrosol. How do you prefer to include it in your routine—through diet or supplements?

  • vegandan

    Member
    January 21, 2025 at 12:58 pm EST

    Very interesting. Another tool in the health toolbox.

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