Safety of Ivermectin

Standard doses of ivermectin (0.2 mg/kg x 1–2 days) have a nearly unparalleled safety profile historically among medicines as evidenced by the following findings:

  • WHO Guidelines for Scabies: “the majority of side effects are minor and transient”
  • Jacques Descotes, Toxicologist and Expert on Safety of Ivermectin: “severe adverse events are unequivocally and exceedingly rare”
  • LiverTox Database: Not considered toxic to the liver
  • Nephrotox Database: Not considered toxic to the kidney
  • PneumoTox: Not considered toxic to the lungs

Safety of High Dose Ivermectin

In COVID-19, particularly with regard to the emerging variants of concern, viral loads are higher and viral replication is thought to be prolonged. Given that ivermectin has