Authors: Copin MC, Parmentier E, Duburcq T, Poissy J, Mathieu D

PMID: 32328726 PMCID: PMC7178098 DOI: 10.1007/s00134-020-06057-8


In their editorial about ‘COVID-19 pneumonia: different respiratory treatment for different phenotypes’ Gattinoni et al. hypothesize a sequence of events in critically ill patients infected by SARS-CoV-2. They describe a type L characterized by a low elastance, a low ventilation to perfusion ratio, a low lung weight and a low lung recruitability. Worsening patients are supposed to progress from type L to type H. Type H is characterized by a high elastance, a high right-to-left shunt, a high lung weight and a high lung recruitability. As Gattinoni and colleagues complete their editorial, “understanding the correct pathophysiology is crucial to establishing the basis for appropriate treatment”.

Keywords: COVID-19, SARS-CoV-2, lung injury

More on: MATH+

More on: COVID-19