Authors: Hinduja A, Moutairou A, Calvet JH

PMID: 33551341 PMCID: PMC7835104 DOI: 10.1016/j.neucli.2021.01.003


Dysautonomia has been reported in COVID-19. Sweat function testing has been proposed to assess autonomic neuropathy. Fifty Indian patients consulting for neurological symptoms participated in this observational study. The NHS questionnaire for neurological symptoms was completed and electrochemical skin conductance was measured using Sudoscan. The 26% of patients with sweat dysfunction i) were older (p = 0.001), ii) were more frequently treated at home (p = 0.008), iii) were more likely to have received antiviral treatment (p = 0.0006), and iv) more frequently reported at least one motor, sensory or autonomic symptom (p = 0.04). This preliminary study suggests that patients with COVID-19 should be screened for dysautonomia.

Keywords: COVID-19; Dysautonomia; Electrochemical skin conductance; Small fiber neuropathy.