Authors: Pujadas E, Chaudhry F, McBride R, Richter F, Zhao S

PMID: 32771081 PMCID: PMC7836878 DOI: 10.1016/S2213-2600(20)30354-4


Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) detection platforms currently report qualitative results. However, technology based on RT-PCR allows for calculation of viral load, which is associated with transmission risk and disease severity in other viral illnesses.1 Viral load in COVID-19 might correlate with infectivity, disease phenotype, morbidity, and mortality. To date, no studies have assessed the association between viral load and mortality in a large patient cohort.2, 3, 4 To our knowledge, we are the first to report on SARS-CoV-2 viral load at diagnosis as an independent predictor of mortality in a large hospitalised cohort (n=1145).

Keywords: SARS-CoV-2, COVID-19

More on: MATH+

More on: COVID-19 | SARS-CoV-2