Authors: Islam MT, Guha B, Hosen S, Alam T, Shahadat S
Nigella sativa and its constitutions including some isolated compounds are the potential sources of remedies of varieties of ailments such as antioxidant, anti–inflammatory, antibacterial, antifungal, antiparasitic and antiprotozoal, antiviral,
cytotoxic, anticancer, neuro–, gastro–, cardio–, hetapto– and nephroprotective activities. In addition, the N. sativa implies beneficiary effects on reproductive, pulmonary and immune systems along with diabetes mellitus (DM), fertility, breast cancer, dermatological complications, dehydration, dyspepsia, osmotic balance and soon. Among the other isolated chemical moieties, thymoquinone (TQ) is a good target for its potential antimicrobial, antimicrobial, anti–inflammatory, chemopreventive, antitumoral and other activities. The N. sativa is evident to promote health in some non–clinical and clinical studies. Otherwise, TQ in a number of animal test systems is evident to produce no negative alterations of the body biomarkers in contrary it improved health quality. This paper depicts a more mechanistic revision on N. sativa and its constitutions. In conclusion, findings on Nigella may be featured as a health jackpot.