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Medical Evidence

Ivermectin

Since October 2020 we regard ivermectin as a core medication in the prophylaxis and treatment of COVID-19. For comprehensive information on ivermectin please refer to the references within our Review of the Emerging Evidence Supporting the Use of Ivermectin in the Prophylaxis and Treatment of COVID-19.

November 16, 2020 | Egypt
Efficacy and safety of ivermectin for treatment and prophylaxis of COVID-19 pandemic
Elgazzar A, Basma H, Shaimaa Abo Y, Basma H, Mohy H, Hany M (Research Square; 100956)
https://doi.org/10.21203/rs.3.rs-100956/v2

November 3, 2020 | India
Role of Ivermectin in the prevention of COVID-19 infection among health care workers in India
A matched case-control study; Behera P, Patro BK, Singh AK, et al. (medRxiv)
https://doi.org/10.1101/2020.10.29.20222661

October 27, 2020 | Iraq
Controlled randomized clinical trial on using ivermectin with doxycycline for treating COVID-19 patients in Baghdad, Iraq
Hashim HA, Maulood MF, Rasheed AM, Fatak DF, Kabah KK, Abdulamir AS (medRxiv)
https://doi.org/10.1101/2020.10.26.20219345

October 22 | Peru
Antiviral and anti-inflammatory properties of ivermectin and its potential use in COVID-19
Portmann-Baracco A, Bryce-Alberti M, Accinelli RA (NCBI/Arch Bronconeumol/ScienceDirect)
https://dx.doi.org/10.1016%2Fj.arbr.2020.06.006

October 12, 2020 | USA
Use of ivermectin is associated with lower mortality in hospitalized patients with COVID-19
Rajter J-C, Sherman MS, Fatteh N, Vogel F, Sacks J, Rajter J-J (ICON study; Chest)
https://doi.org/10.1016/j.chest.2020.10.009

October 2020 | Peru
Real-world evidence: The case of Peru. Causality between ivermectin and COVID-19 infection fatality rate
Juan Chamie (ResearchGate)
https://www.researchgate.net/publication/344469305_Real-World_Evidence_The_Case_of_Peru_Causality_be…

August 24, 2020 | Bangladesh
Clinical trial of ivermectin plus doxycycline for the treatment of COVID-19 infection
Dr. Reaz Mahmud, Dhaka Medical College (ClinicalTrials.gov; NCT04523831)
https://clinicaltrials.gov/ct2/show/NCT04523831

June 11, 2020 | Argentina
Usefulness of topical ivermectin and carrageenan to prevent contagion of COVID-19 (IVERCAR)
Hector E Carvallo, Eurnekian Public Hospital (ClinicalTrials.gov; NCT04425850)
https://clinicaltrials.gov/ct2/show/NCT04425850

June 9, 2020 | Egypt
Prophylactic Ivermectin in COVID-19 Contacts
Waheed Shouman, Zagazig University (ClinicalTrials.gov; NCT04422561)
https://clinicaltrials.gov/ct2/show/NCT04422561

June 2020 | Australia
The FDA-approved drug ivermectin inhibits the replication of SARS-CoV-2 in vitro
Caly L, Druce JD, Catton MG, Jans DA, Wagstaff KM (Antiviral Res.; 178:104787)
https://doi.org/10.1016/j.antiviral.2020.104787