I-MASK+ Prophylaxis & Early Outpatient Treatment Protocol

This page contains the I-MASK+ Prophylaxis & Early Outpatient Treatment Protocol for COVID-19 with guidance on the timing and doses of each component medication. The I-MASK+ Protocol complements our  MATH+ Hospital Treatment Protocol for Covid-19 from March 2020, which is intended for hospitalized patients. Both are physiologic-based combination treatment regimens developed by leaders in critical care medicine. All component medicines are FDA-approved, inexpensive, readily available and have been used for decades with well-established safety profiles.

The protocol document is currently available for download in English, Italian, German and French, see links below (translations to Spanish and Portuguese will follow). This is not a medical advice, but a recommendation – please consult your doctor, share the information on this website with her/him, and listen. Please regard our informations on the  I-MASK+ main page, as well as our  Disclaimers.

Please check this page regularly for updates – The dosings in our protocols may be updated as further scientific studies emerge.

Current I-MASK+ protocol: version 9, updated on Feb 25, 2021.